Results 61 to 70 of about 1,668,775 (361)

Advances in Electrospun Nerve Guidance Conduits for Engineering Neural Regeneration [PDF]

, 2022
Injuries to the peripheral nervous system result in devastating consequences with loss of motor and sensory function and lifelong impairments. Current treatments have largely relied on surgical procedures, including nerve autografts to repair damaged ...
James A. St John, Behtaj, Sanaz, Sanaz Behtaj, Ekberg, Jenny AK, St John, James A, Jenny A. K. Ekberg   +5 more
core   +1 more source

Endocannabinoid System Modulates Glial Responses and Motoneuron Preservation After Spinal Cord Ventral Root Axotomy

Neuroglia
Background/Objectives: Injuries to spinal ventral roots induce complex retrograde reactions that compromise motoneuron survival, synaptic organization, and glial responses, ultimately limiting the potential for regeneration.
Caroline Machado Tomazelli, Alexandre Leite Rodrigues de Oliveira, Luciana Politti Cartarozzi   +2 more
doaj   +1 more source

Intradiscal injection for the management of low back pain

JOR Spine, 2022
Low back pain (LBP) is a common clinical problem and a major cause of physical disability, imposing a prominent socioeconomic burden. Intervertebral disc degeneration (IDD) has been considered the main cause of LBP.
Fu Zhang, Songjuan Wang, Baoliang Li, Wei Tian, Zhiyu Zhou, Shaoyu Liu   +5 more
doaj   +1 more source

Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation

Frontiers in Cell and Developmental Biology, 2021
Transthyretin (TTR), a plasma and cerebrospinal fluid protein, increases axon growth and organelle transport in sensory neurons. While neurons extend their axons, the microtubule (MT) cytoskeleton is crucial for the segregation of functional compartments
Jessica Eira, Jessica Eira, Joana Magalhães, Nídia Macedo, Maria Elena Pero, Maria Elena Pero, Thomas Misgeld, Mónica M. Sousa, Francesca Bartolini, Márcia A. Liz   +9 more
doaj   +1 more source

Spatial pattern of nerve differentiation in Hydra is due to a pattern of nerve commitment [PDF]

, 1981
The pattern of nerve differentiation along the body column of Hydra was investigated. Nerve precursors in late S phase were labeled with [3H]thymidine and their distribution compared with that of newly differentiated nerves.
G. Venugopal, Venugopal, G., Charles N. David, David, Charles N.   +3 more
core   +1 more source

Neuroprotection and immunomodulation after treatment with NeuroBoost and NeuroHeal following ventral root crush in mice

IBRO Neuroscience Reports
Pharmacological immunomodulation can prevent neuronal loss and reactive gliosis after injuries to spinal nerve roots. NeuroBoost (NB) and NeuroHeal (NH) were used to compare their effects on neuronal survival, glial and immune response, and functional ...
Lilian de Oliveira Coser, Maria Fernanda Vannucci, Júlia Lombardi, Luciana Politti Cartarozzi, Alexandre Leite Rodrigues de Oliveira   +4 more
doaj   +1 more source

REGENERATION OF PERIPHERAL NERVES [PDF]

The Journal OF Nervous and Mental Disease, 1922
n ...
openaire   +2 more sources

Peripheral Nerve Regeneration and Muscle Reinnervation

International Journal of Molecular Sciences, 2020
Injured peripheral nerves but not central nerves have the capacity to regenerate and reinnervate their target organs. After the two most severe peripheral nerve injuries of six types, crush and transection injuries, nerve fibers distal to the injury site
T. Gordon
semanticscholar   +1 more source

ATF3 upregulation in glia during Wallerian degeneration: differential expression in peripheral nerves and CNS white matter [PDF]

, 2004
Background: Many changes in gene expression occur in distal stumps of injured nerves but the transcriptional control of these events is poorly understood.
Coffin, RS, Hossain-Ibrahim Kismet, Mason, MRJ, Lieberman AR, Lieberman, AR, Mason Matthew RJ, Hossain-Ibrahim, K, David Hunt, Winterbottom, J, Anderson, PN, Hunt David, AR Lieberman, Kismet Hossain-Ibrahim, Anderson PN, Coffin Robert S, Hunt, D, PN Anderson, Matthew RJ Mason, Robert S Coffin, Winterbottom Julia, Julia Winterbottom   +20 more
core   +1 more source

Combination of Adult Mesenchymal Stem Cell Therapy and Immunomodulation with Dimethyl Fumarate Following Spinal Cord Ventral Root Repair

Biology
Spinal cord injury results in significant motor and sensory loss. In the experimental ventral root avulsion (VRA) model, the ventral (motor) roots are disconnected from the spinal cord surface, disrupting contact between spinal motoneurons and muscle ...
Paula Regina Gelinski Kempe, Mateus Vidigal de Castro, Lilian de Oliveira Coser, Luciana Politti Cartarozzi, Benedito Barraviera, Rui Seabra Ferreira, Alexandre Leite Rodrigues de Oliveira   +6 more
doaj   +1 more source