Results 91 to 100 of about 784,496 (306)

Peripheral Facial Nerve Axotomy in Mice Causes Sprouting of Motor Axons Into Perineuronal Central White Matter: Time Course and Molecular Characterization [PDF]

open access: yes, 2010
Generation of new axonal sprouts plays an important role in neural repair In the current study, we examined the appearance, composition and effects of gene deletions on intrabrainstem sprouts following peripheral facial nerve axotomy Axotomy was followed
Werner, A   +62 more
core   +1 more source

Desert Plant Inspired Hierarchical Nanofibrous Membranes for Integrated Solar Desalination and Heavy Metal Remediation

open access: yesAdvanced Functional Materials, EarlyView.
An Alhagi maurorum inspired hierarchical composite membrane (NFCu) was developed by integrating heavy metal remediation and solar‐driven interfacial evaporation in a single platform. Beyond the photothermal effect, a localized photocatalytic process is realized on the CuO surface, deepening the mechanistic understanding of light–matter–water ...
Yuqiong He   +9 more
wiley   +1 more source

Cross species reproducibility of MRI radiomics features enables intervertebral disc degeneration assessment in experimental monkeys

open access: yesScientific Reports
Experimental monkeys serve as a bridge between basic research and clinical medicine. Accurately assessing the degree of intervertebral disc degeneration (IVDD) in experimental monkeys is crucial for further intervertebral disc related research in these ...
Jianmin Wang   +14 more
doaj   +1 more source

Spinal hypermobility accelerates ossification in posterior longitudinal ligaments: insights from an in vivo mouse model

open access: yesFrontiers in Physiology
IntroductionOssification of the posterior longitudinal ligaments (OPLL) is characterized by heterotopic ossification in the posterior longitudinal ligament of spine.
Tao Tang   +15 more
doaj   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu   +14 more
wiley   +1 more source

Complement components of nerve regeneration conditioned fluid influence the microenvironment of nerve regeneration

open access: yesNeural Regeneration Research, 2016
Nerve regeneration conditioned fluid is secreted by nerve stumps inside a nerve regeneration chamber. A better understanding of the proteinogram of nerve regeneration conditioned fluid can provide evidence for studying the role of the microenvironment in
Guang-shuai Li   +5 more
doaj   +1 more source

Nerve tissue engineering using blends of poly(3-hydroxyalkanoates) for peripheral nerve regeneration [PDF]

open access: yes, 2015
The only types of polyhydroxyalkanoates (PHAs) that have been explored for use in nerve regeneration are poly(3-hydroxybutyrate), P(3HB), and poly(3- hydroxybutyrate-co-3-hydroxyhexanoate) (P(3HB-co-3HHx)). However, nerve regeneration induced by these
Lizarraga Valderrama, L.   +14 more
core   +1 more source

Charting Morphotoxicity With Complementary Embryo Models

open access: yesAdvanced Healthcare Materials, EarlyView.
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx   +9 more
wiley   +1 more source

Development of a mouse model of chronic ventral spinal cord compression: Neurobehavioral, radiological, and pathological changes

open access: yesJOR Spine
Objectives The main objective of this study was to establish a mouse model of spinal ligament ossification to simulate the chronic spinal cord compression observed in patients with ossification of the posterior longitudinal ligament (OPLL).
Zhongyuan He   +9 more
doaj   +1 more source

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