Results 1 to 10 of about 227,893 (266)

Unraveling proteomic signatures and neuroinflammatory networks in a CCI rat model of early sciatica: insights for neuropathic pain mechanisms [PDF]

open access: yesFrontiers in Molecular Neuroscience
IntroductionSciatica is a prevalent and highly debilitating condition that is clinically characterized by pain radiating along the distribution of the sciatic nerve.
Xingjuan Li   +7 more
doaj   +2 more sources

Recovery of sweet taste preference in adult rats following bilateral chorda tympani nerve transection [PDF]

open access: yesPeerJ, 2022
Background Numerous studies have noted the effect of chorda tympani (CT) nerve transection on taste sensitivity yet very few have directly observed its effects on taste receptor and taste signaling protein expressions in the tongue tissue.
Andrew Padalhin   +7 more
doaj   +2 more sources

Transection injury differentially alters the proteome of the human sural nerve

open access: yesPLoS ONE, 2022
Regeneration after severe peripheral nerve injury is often poor. Knowledge of human nerve regeneration and the growth microenvironment is greatly lacking.
Monica J. Chau   +7 more
doaj   +2 more sources

Using a Transection Paradigm to Enhance the Repair Mechanisms of an Investigational Human Cell Therapy

open access: yesCell Transplantation, 2022
One promising strategy in cell therapies for Parkinson’s disease (PD) is to harness a patient’s own cells to provide neuroprotection in areas of the brain affected by neurodegeneration. No treatment exists to replace cells in the brain.
Monica J. Chau   +6 more
doaj   +1 more source

Immunohistochemical localization of nerve injury-induced protein-1 in mouse tissues [PDF]

open access: yesAnatomy & Cell Biology, 2019
Nerve injury-induced protein (Ninjurin)-1 is a cell adhesion molecule that is upregulated in neurons and Schwann cells after transection injury in rats. In this study, we investigated the localization of Ninjurin-1 in various tissues, including the cerebrum, sciatic nerve, spleen, lung, stomach, ileum, colon, liver, pancreas, kidney, testis, and skin ...
Poornima Ekanayake   +4 more
openaire   +2 more sources

Cell-free therapy based on extracellular vesicles: a promising therapeutic strategy for peripheral nerve injury

open access: yesStem Cell Research & Therapy, 2023
Peripheral nerve injury (PNI) is one of the public health concerns that can result in a loss of sensory or motor function in the areas in which injured and non-injured nerves come together.
Mojdeh Salehi Namini   +6 more
doaj   +1 more source

Collagen‐rich deposit formation in the sciatic nerve after injury and surgical repair: A study of collagen‐producing cells in a rabbit model

open access: yesBrain and Behavior, 2020
Introduction Posttraumatic scarring of peripheral nerves produces unwanted adhesions that block axonal growth. In the context of surgical nerve repair, the organization of the scar tissue adjacent to conduits used to span the gap between the stumps of ...
Jolanta Fertala   +5 more
doaj   +1 more source

Spike Generators and Cell Signaling in the Human Auditory Nerve: An Ultrastructural, Super-Resolution, and Gene Hybridization Study

open access: yesFrontiers in Cellular Neuroscience, 2021
Background: The human auditory nerve contains 30,000 nerve fibers (NFs) that relay complex speech information to the brain with spectacular acuity. How speech is coded and influenced by various conditions is not known.
Wei Liu   +10 more
doaj   +1 more source

Skin cornification proteins provide global link between ROS detoxification and cell migration during wound healing. [PDF]

open access: yesPLoS ONE, 2010
Wound healing is a complex dynamic process characterised by a uniform flow of events in nearly all types of tissue damage, from a small skin scratch to myocardial infarction.
Wilbert P Vermeij, Claude Backendorf
doaj   +1 more source

A Bioinspired Self‐Healing Conductive Hydrogel Promoting Peripheral Nerve Regeneration

open access: yesAdvanced Science, 2023
The development of self‐healing conductive hydrogels is critical in electroactive nerve tissue engineering. Typical conductive materials such as polypyrrole (PPy) are commonly used to fabricate artificial nerve conduits.
Hongyun Xuan   +8 more
doaj   +1 more source

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