Results 211 to 220 of about 203,319 (294)

Cancer-Related PRUNE2 Protein Is Associated with Nucleotides and Is Highly Expressed in Mature Nerve Tissues [PDF]

Journal of Molecular Neuroscience, 2011
Human PRUNE is thought to enhance the metastasis of tumor cells. We found that a hypothetical paralog of PRUNE, PRUNE2, binds to 8-oxo-GTP, an oxidized form of GTP. Hypothetical PRUNE2 gene consists of C9orf65 and BMCC1/BNIPXL, both of which are malignant tumor-associated genes.
Akira Nakagawara, Kunihiko Sakumi, Yoichi Nakanishi, Teruaki Iyama, Yusaku Nakabeppu, Koichi Takayama, Daisuke Tsuchimoto, Eiji Iwama   +7 more
openaire   +3 more sources

Changes of cytoskeletal proteins in nerve tissues and serum of rats treated with 2,5-hexanedione

Toxicology, 2008
To investigate the mechanisms and biomarker of the neuropathy induced by 2,5-hexanedione (HD), male Wistar rats were administrated HD at dosage of 200 or 400mg/kg for 8 weeks (five-times per week). All rats were sacrificed after 8 weeks of treatment and the cerebrum cortex (CC), spinal cord (SC) and sciatic nerves (SN) were dissected, homogenized and ...
Keqin Xie, Qingshan Wang, Fuyong Song, Li-yan Hou, Cui-Li Zhang   +4 more
openaire   +3 more sources

Expression changes of apoptotic-related proteins in nerve tissues of rats treated with allyl chloride

Toxicology, 2007
Allyl chloride (AC) is widely used in industries as raw material and has been reported to produce occupational peripheral neuropathies in man chronically exposure to it. Although many studies have been done addressing to it, the mechanisms still remain unclear.
Fuyong Song, Li-yan Hou, Qingshan Wang, Xiulan Zhao, Keqin Xie   +4 more
openaire   +4 more sources

Whole intact tissue electrophoresis of nerve proteins

Journal of Neuroscience Methods, 1993
We describe a rapid and simple method for analyzing proteins along the length of a nerve tissue using sodium dodecylsulfate-polyacrylamide gel electrophoresis (SDS-PAGE). A long length of nerve tissue is placed on a slab gel, layered with SDS-buffer, and electrophoresed.
George D. Bittner, Rebecca A. Sheller
openaire   +4 more sources

A comparison of demyelinating and myelination-inhibiting factor induction by whole peripheral nerve tissue and P2 protein

Brain Research, 1981
Sera from rabbits sensitized with whole bovine spinal roots demyelinated and inhibited myelination in both peripheral and central nervous system tissue cultures. Antisera directed against the peripheral nerve myelin basic protein, P2, demonstrated no antimyelin activity in vitro.
Marian W. Kies, Fredrick J. Seil, Martha L. Bacon   +2 more
openaire   +4 more sources

2,5-hexanedione (HD) treatment alters calmodulin, Ca2+/calmodulin-dependent protein kinase II, and protein kinase C in rats' nerve tissues

Toxicology and Applied Pharmacology, 2008
Calcium-dependent mechanisms, particularly those mediated by Ca(2+)/calmodulin (CaM)-dependent protein kinase II (CaMKII), have been implicated in neurotoxicant-induced neuropathy. However, it is unknown whether similar mechanisms exist in 2,5-hexanedione (HD)-induced neuropathy.
Qingshan Wang, Li-Yan Hou, Cui-Li Zhang, Xiulan Zhao, Keqin Xie, Sufang Yu   +5 more
openaire   +4 more sources

Organized Cultures of Nerve Tissue: A Novel Model System for Studies of Lipid Protein Interaction on the Functional Level

, 1985
Organized fragments of grey matter of cerebral cortex (CC) maintained in vitro during cell maturation in the explant culture assembly are presented as a novel tool for studies on the functional impact of membrane phospholipids (PL). PL have been found to affect two transport systems and one receptor system.
M. Giesing
openaire   +3 more sources

Immunochemical assay of a protein characteristic of the nervous tissue in embryonic sensory ganglia cultured with and without nerve growth factor

Brain Research, 1968
Pietro U. Angeletti, Pietro U. Angeletti, Antonia Zanini, Antonia Zanini   +3 more
openaire   +4 more sources

[Effect of ATP on protein synthesis in cultured nerve tissue of the edible snail].

Tsitologiia, 1979
External ATP in concentrations of 10(-6)--10(-3) M is shown to stimulate the label incorporation from intracellular labeled pool of 14C-leucine into proteins of mollusc nervous tissue. The maximum effect (by 45% higher than in control) is observed at the 10(-5) ATP concentration.
T I, Smolikhina, M A, Kostenko
openaire   +2 more sources

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TISSUE EXPRESSION OF NEURONAL PROTEINS DURING SCIATIC NERVE REGENERATION AND INFLUENCE OF DIFFERENT SPECTRUM LASER RADIATION

Polski Merkuriusz Lekarski, 2023
Aim: To determine the effect of laser irradiation of different spectrum on the expression of neuronal proteins (GFAP, S100, NSE and NF-L) in the sciatic nerve during its regeneration after crossing and surgical suturing. Materials and methods: The experiment was performed on 60 laboratory rats of the Wistar line (200-250 g) with crossing of the left ...
Zinovii M, Yashchyshyn, Iryna B, Kreminska, Markiian I, Medynskyi, Volodymyr M, Fedorak, Serhii V, Ziablitsev, Olena O, Diadyk, Larysa Ya, Fedoniuk   +6 more
openaire   +2 more sources