Background: The human auditory nerve contains 30,000 nerve fibers (NFs) that relay complex speech information to the brain with spectacular acuity. How speech is coded and influenced by various conditions is not known.
Wei Liu+10 more
doaj +1 more source
Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates [PDF]
Perturbations in skeletal muscle metabolism have been reported for a variety of neuromuscular diseases. However, the role of metabolism after constriction injury to a nerve and the associated muscle atrophy is unclear.
Afzal, Shoaib+3 more
core +2 more sources
Skin cornification proteins provide global link between ROS detoxification and cell migration during wound healing. [PDF]
Wound healing is a complex dynamic process characterised by a uniform flow of events in nearly all types of tissue damage, from a small skin scratch to myocardial infarction.
Wilbert P Vermeij, Claude Backendorf
doaj +1 more source
EMSCs‐Seeded Micro‐Stripe Patterned Polycaprolactone Promoting Sciatic Nerve Regeneration
Transplantation of a synthetic polymer nerve conduit carrying stem cells is promising for treating peripheral nerve injury. In this study, a micropatterned inner surface of polycaprolactone (PCL) nerve conduit cellularized with nasal respiratory mucosa ...
Naiyan Lu+10 more
doaj +1 more source
A Myelin Proteolipid Protein-LacZ Fusion Protein Is Developmentally Regulated and Targeted to the Myelin Membrane in Transgenic Mice [PDF]
Transgenic mice were generated with a fusion gene carrying a portion of the murine myelin proteolipid protein (PLP) gene, including the first intron, fused to the E. coli LacZ gene.
Duchala, Cynthia S.+3 more
core +2 more sources
Alarmins in frozen shoulder: a molecular association between inflammation and pain [PDF]
Background: The pathophysiological mechanisms behind proliferation of fibroblasts and deposition of dense collagen matrix in idiopathic frozen shoulder remain unclear.
Akbar, Moeed+10 more
core +1 more source
Background and Objective: Radiofrequency ablation (RFA) is a safe and less invasive technique that uses an electric current to damage nerve tissue to stop it from sending pain signals.
Li Su+12 more
doaj +1 more source
Fossilization transforms vertebrate hard tissue proteins into N-heterocyclic polymers
Vertebrate hard tissues consist of mineral crystallites within a proteinaceous scaffold that normally degrades post-mortem. Here we show, however, that decalcification of Mesozoic hard tissues preserved in oxidative settings releases brownish stained ...
J. Wiemann+6 more
semanticscholar +1 more source
Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue. [PDF]
Two different monoclonal antibodies, characterized initially as binding synaptic terminal regions of rat brain, bind a 65,000-dalton protein, which is exposed on the outer surface of brain synaptic vesicles. Immunocytochemical experiments at the electron
Matthew, WD, Reichardt, LF, Tsavaler, L
core +2 more sources
Scatterometry Measurements with Scattered Light Imaging Enable New Insights into the Nerve Fiber Architecture of the Brain [PDF]
The correct reconstruction of individual (crossing) nerve fibers is a prerequisite when constructing a detailed network model of the brain. The recently developed technique Scattered Light Imaging (SLI) allows the reconstruction of crossing nerve fiber pathways in whole brain tissue samples with micrometer resolution: The individual fiber orientations ...
arxiv +1 more source