Results 61 to 70 of about 2,544,571 (298)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Optic nerve hypoplasia in the fetal alcohol syndrome:a mouse model [PDF]
, 1995 Optic nerve hypoplasia is commonly observed in children affected by the fetal alcohol syndrome, and is believed to contribute to their poor visual acuity.
Dhillon, Baljean +3 more
core
Restoration of the function of the sciatic nerve and its branches after trauma
Medicinski GlasnikAim To investigate the efficacy of various methods for restoring the sciatic nerve and its branches after traumatic injuries to develop optimal treatment strategies, improve functional outcomes, and enhance patients' quality of life.Methods A ...
Alimkhan Khalimov +7 more
doaj +1 more source
Nerve Transfer Versus Tendon Transfer for Isolated Radial Nerve Palsy
HANDBackground: Reconstructive options for high radial nerve injuries include tendon transfer (TT) and nerve transfer (NT), each with distinct advantages and limitations. This prospective, randomized clinical trial compared the outcomes of TT and NT in 21 patients with isolated radial nerve injuries.
Tarek Abdalla El-Gammal +2 more
openaire +3 more sources
Nerve transfers for treatment of isolated axillary nerve injuries [PDF]
Plastic Surgery, 2015 Background The most common neurological defect in traumatic anterior glenohumeral dislocation is isolated axillary nerve palsy. Most recover spontaneously; however, some have persistent axillary neuropathy. An intact rotator cuff may compensate for an isolated axillary nerve injury; however, given the high rate ...
Margie, Wheelock +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Philippine Journal of OrthopaedicsBackground. Nerve reconstructions for C5 to C8 brachial plexus injuries are challenging due to the extent of injury and paucity of nerve donors. Objective.
Emmanuel Estrella +1 more
doaj +1 more source
Neural Regeneration Research, 2019 Contralateral C7 nerve transfer surgery is one of the most important surgical techniques for treating total brachial plexus nerve injury. In the traditional contralateral C7 nerve transfer surgery, the whole ulnar nerve on the paralyzed side is harvested
Guang-Hui Hong +5 more
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source