Results 101 to 110 of about 24,153,656 (297)

Saturable Active Efflux by P-Glycoprotein and Breast Cancer Resistance Protein at the Blood-Brain Barrier Leads to Nonlinear Distribution of Elacridar to the Central Nervous System [PDF]

, 2013
Ramola Sane, Sagar Agarwal, Rajendar K. Mittapalli, William F. Elmquist   +3 more
openalex   +1 more source

A comparative study of multimodal magnetic resonance in the differential diagnosis of acquired immune deficiency syndrome related primary central nervous system lymphoma and infection [PDF]

, 2020
Jing Li, Ming Xue, Shuo Yan, Chunshuang Guan, Ruming Xie, Budong Chen   +5 more
openalex   +1 more source

Functional Characterization and Pathogenicity Classification of PRRT2 Splice Variants in PRRT2‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Paroxysmal kinesigenic dyskinesia (PKD) is the most common hereditary paroxysmal movement disorder. The PRRT2 gene is the first identified causative gene and accounts for the majority of PKD. In this study, we investigated the pathogenicity of PRRT2 variants in the splice regions. Methods Patients with clinically suspected PKD and no
Jiao‐Jiao Xu, Yu‐Lan Chen, Wan‐Bing Sun, Hong‐Fu Li, Zhi‐Ying Wu, Dian‐Fu Chen   +5 more
wiley   +1 more source

STRUCTURAL AND FUNCTIONAL ALTERATIONS AT THE BLOOD-BRAIN BARRIER IN A MOUSE MODEL FOR MCT8 DEFICIENCY

IBRO Neuroscience Reports, 2023
Ana Montero-Pedrazuela, Marina Guillén-Yunta, Víctor Valcárcel Hernández, Ana Guadaño Ferraz   +3 more
doaj   +1 more source

A nomenclature consensus for nervous system organoids and assembloids

Nature, 2022
S. Pașca, P. Arlotta, Helen S. Bateup, J. G. Camp, S. Cappello, F. Gage, Jurgen Knoblich, A. Kriegstein, Madeline A. Lancaster, G. Ming, A. Muotri, In-Hyun Park, O. Reiner, Hongjun Song, L. Studer, S. Temple, G. Testa, Barbara Treutlein, F. Vaccarino   +18 more
semanticscholar   +1 more source

Quantity and Volume of Perivascular Spaces Are Inversely Associated With Multiple Sclerosis Relative to Cerebrovascular Disease and Migraine

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To quantify the number and volume of whole brain perivascular spaces (PVS) using a detection and segmentation algorithm in participants with multiple sclerosis (MS) and patients with disorders mimicking MS known to potentially influence PVS, such as cerebrovascular disease.
Elle M. Levit, Elizabeth A. Horwath, Daniel L. Schwartz, Lisa C. Silbert, Russell T. Shinohara, Andrew J. Solomon   +5 more
wiley   +1 more source

The Diverse Neuromuscular Spectrum of VPS13A Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective VPS13A disease (chorea‐acanthocytosis) is a rare neurodegenerative disorder caused by biallelic variants in VPS13A, typically presenting with hyperkinetic movement disorders, while neuromuscular signs are often mild. The aim of the project was to investigate the frequency and severity of neuromuscular impairment in VPS13A disease ...
Anne Buchberger, Evamaria Riedel, Marie Hackenberg, Alexander Mensch, Stefanie Beck‐Woedl, Joohyun Park, Tobias B. Haack, Bernhard Haslinger, Jan Kirschke, Holger Prokisch, Andreas Hermann, Christian Mawrin, Adrian Danek, Benedikt Schoser, Kevin Peikert, Marcus Deschauer, Isabell Cordts   +16 more
wiley   +1 more source

LBA3 Compartmental radioimmunotherapy (cRIT) 131I-OMBURTAMAB in patients with neuroblastoma (NB) central nervous system (CNS) and/or leptomeningeal (LM) metastases: Updated results from pivotal Trial 101

, 2022
Ellen M. Basu, J. Mora, K. Streby, M. Bear, H. Sano, A. Marachelian, D. Harrison, K. Nysom, N. Pandit-Taskar, P. Zanzonico, S. Fabricius, M. During, J.R. Nielsen, K. Kramer   +13 more
openalex   +1 more source

Nervous system involvement after infection with COVID-19 and other coronaviruses

Brain, behavior, and immunity, 2020
Yeshun Wu, Xiaolin Xu, Zijun Chen, Jiahao Duan, K. Hashimoto, Ling Yang, Cunming Liu, Chun Yang   +7 more
semanticscholar   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source