Results 101 to 110 of about 3,017,282 (362)

TSPO deficiency promotes the progression of malignant peripheral sheath tumors by regulating the G2/M phase of the cell cycle via CDK1

Scientific Reports
Malignant peripheral nerve sheath tumors (MPNSTs) are highly aggressive Schwann cell-derived sarcomas that are sporadic or associated with Neurofibromatosis 1 (NF1) gene mutations. Traditional therapies are usually ineffective for treating MPNSTs, so new
Xingnan Zhang, Chenhao Hu, Shengqiao Sun, Chao Guo, Yakun Bu, Zicong Wang, Zewei Liu, Xiaoli Zhang, Dezhi Li, Song Liu   +9 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Typical CIDP, distal variant CIDP, and anti-MAG antibody neuropathy: An ultra-high frequency ultrasound comparison of nerve structure

Scientific Reports
To date, little is known about the usefulness of ultra-high frequency ultrasound (UHF-US, 50–70 MHz) in clinical practice for the diagnosis of dysimmune neuropathies.
Angela Puma, Nicolae Grecu, Raluca Ș. Badea, Adeline Morisot, Roxana Zugravu, Mihai B. Ioncea, Michele Cavalli, Oana Lăcătuș, Andra Ezaru, Chorfa Hacina, Luisa Villa, Charles Raffaelli, Nicolas Azulay, Sabrina Sacconi   +13 more
doaj   +1 more source

Concentration of immunoglobulin free light chains in cerebrospinal fluid in the diagnosis of multiple sclerosis

Неврология, нейропсихиатрия, психосоматика
Objective: to determine the sensitivity and specificity of method of determining the concentration of immunoglobulin free light chains (FLCs) in cerebrospinal fluid (CSF) in the diagnosis and differential diagnosis of multiple sclerosis (MS).Material and
Sh. R. Nabiev, S. A. Dzhukkaeva, M. Sh. Asvedov, D. E. Prokhorov, E. V. Popova, V. V. Grinyuk, P. R. Magomadova, A. R. Apevalova, O. N. Voskresenskaya   +8 more
doaj   +1 more source

Diagnosis and treatment of dizziness in outpatient practice

Неврология, нейропсихиатрия, психосоматика, 2015
Objective: to study the causes of dizziness and instability in patients during an outpatient specialized appointment and to analyze and improve typical management tactics for these patients. Patients and methods.
L. M. Antonenko, N. V. Bestuzheva, V. A.
 Parfenov   +2 more
doaj   +1 more source

Rapid testing leads to the underestimation of the scrapie prevalence in an affected sheep and goat flock [PDF]

, 2007
To obtain a more detailed understanding of the prevalence of classical scrapie infections in a heavily affected German sheep flock (composed of 603 sheep and 6 goats), we analysed 169 sheep and 6 goats that carried the genotypes susceptible to the ...
Bellmann, Steffi, Buda, Silke, Budras, Klaus-Dieter, Buschmann, Anne, Erhardt, Georg, Fries, Reinhard, Groschup, Martin H., Hoffmann, Christine, Knobloch, Hartmut, Reckling, Karl-Friedrich, Reckzeh, Claudia   +10 more
core   +2 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

N-Pep-Zn Improves Cognitive Functions and Acute Stress Response Affected by Chronic Social Isolation in Aged Spontaneously Hypertensive Rats (SHRs)

Biomedicines
Background/Objectives: Aging and chronic stress are regarded as the most important risk factors of cognitive decline. Aged spontaneously hypertensive rats (SHRs) represent a suitable model of age-related vascular brain diseases. The aim of this study was
Mikhail Y. Stepanichev, Mikhail V. Onufriev, Yulia V. Moiseeva, Olga A. Nedogreeva, Margarita R. Novikova, Pavel A. Kostryukov, Natalia A. Lazareva, Anna O. Manolova, Diana I. Mamedova, Victoria O. Ovchinnikova, Birgit Kastberger, Stefan Winter, Natalia V. Gulyaeva   +12 more
doaj   +1 more source

Spine and Spinal Cord Injuries on the Basis of Medical Documentation

Pielęgniarstwo Neurologiczne i Neurochirurgiczne, 2014
Introduction. The progressive mechanisation of work in every area of life and the rapid development of means of transport have a major impact on the steadily increasing number of injuries.
Joanna Rosińczuk, Paweł Pietralik, Łukasz Wojciechowicz, Aleksandra Kołtuniuk   +3 more
doaj   +1 more source

Distribution of α7 Nicotinic Acetylcholine Receptor Subunit mRNA in the Developing Mouse. [PDF]

, 2019
Homomeric α7 nicotinic acetylcholine receptors (nAChRs) are abundantly expressed in the central and peripheral nervous system (CNS and PNS, respectively), and spinal cord.
Broide, Ron S, Chen, Yling, Leslie, Frances M, Winzer-Serhan, Ursula H   +3 more
core   +1 more source