Results 31 to 40 of about 2,663,952 (341)
Antibody-mediated central nervous system diseases [PDF]
Brain and Neuroscience Advances, 2018 Antibody-mediated central nervous system diseases are a relatively new area of clinical neuroscience with growing impact. Their recognition has challenged the dogma of the blood–brain barrier preventing antibody access into the central nervous system. The antibodies discovered so far are mainly against neurotransmitter receptors (e.g.
Giannoccaro MP, Crisp SJ, Vincent A.
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Glymphatic System Dysfunction in Central Nervous System Diseases and Mood Disorders
Frontiers in Aging Neuroscience, 2022 The glymphatic system, a recently discovered macroscopic waste removal system in the brain, has many unknown aspects, especially its driving forces and relationship with sleep, and thus further explorations of the relationship between the glymphatic ...
Dianjun Zhang, Xinyu Li, Baoman Li
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A Review on Lactoferrin and Central Nervous System Diseases
Cells, 2021 Central nervous system (CNS) diseases are currently one of the major health issues around the world. Most CNS disorders are characterized by high oxidative stress levels and intense inflammatory responses in affected tissues.
Yu-qi Li, Chuang Guo
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The Role of the Effects of Autophagy on NLRP3 Inflammasome in Inflammatory Nervous System Diseases
Frontiers in Cell and Developmental Biology, 2021 Autophagy is a stable self-sustaining process in eukaryotic cells. In this process, pathogens, abnormal proteins, and organelles are encapsulated by a bilayer membrane to form autophagosomes, which are then transferred to lysosomes for degradation ...
Shizhen Zhao +3 more
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Microglia lactylation in relation to central nervous system diseases. [PDF]
Neural Regen ResThe development of neurodegenerative diseases is closely related to the disruption of central nervous system homeostasis. Microglia, as innate immune cells, play important roles in the maintenance of central nervous system homeostasis, injury response ...
Yang H +7 more
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Drug Delivery and Translational Research, 2021 Exosomes are extracellular vesicles with the diameter ranging from 50 to 100 nm and are found in different body fluids such as blood, cerebrospinal fluid (CSF), urine and saliva. Like in case of various diseases, based on the parent cells, the content of
Gayatri Gopal Shetgaonkar +5 more
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Plumbagin inhibits growth of gliomas in vivo via suppression of FOXM1 expression
Journal of Pharmacological Sciences, 2015 Plumbagin is a natural compound that is isolated from the root of the medicinal plant Plumbago zeylanica L. Based on a previous in vitro study performed by our group, which demonstrated the effectiveness of plumbagin against glioma cells, we further ...
Mingshan Niu +9 more
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Cancer Cell International, 2020 Background Activation of nuclear factor-kappa B (NF-κΒ) through DNA damage is one of the causes of tumor cell resistance to radiotherapy. Chromosome region 1 (CRM1) regulates tumor cell proliferation, drug resistance, and radiation resistance by ...
Xuejiao Liu +12 more
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Scientific Reports, 2021 Molluscs are one of the sources of biologically active substances, which are now intensively studied, especially for their anti-cancer properties. Malignant melanoma originates from melanocytes, develops very quickly and is associated with poor prognosis.
Leśków Anna +3 more
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The Biological Activity of 3-O-Acetyl-11-keto-β-Boswellic Acid in Nervous System Diseases
Neuromolecular medicine, 2022 Frankincense is a hard gelatinous resin exuded by Boswellia serrata. It contains a complex array of components, of which acetyl-11-keto-beta-boswellic acid (AKBA), a pentacyclic triterpenoid of the resin class, is the main active component.
Yuqing Gong +8 more
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