Results 31 to 40 of about 2,814,068 (394)

The Role of the Effects of Autophagy on NLRP3 Inflammasome in Inflammatory Nervous System Diseases

open access: yesFrontiers in Cell and Developmental Biology, 2021
Autophagy is a stable self-sustaining process in eukaryotic cells. In this process, pathogens, abnormal proteins, and organelles are encapsulated by a bilayer membrane to form autophagosomes, which are then transferred to lysosomes for degradation ...
Shizhen Zhao   +3 more
semanticscholar   +1 more source

Neurotoxicity [PDF]

open access: yes, 2014
Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust   +15 more
core   +2 more sources

Delayed diagnosis of the neuromyelitis optica spectrum disorder

open access: yesНеврология, нейропсихиатрия, психосоматика, 2023
Neuromyelitis optica spectrum disorders (NMOSD) are a group of autoimmune inflammatory demyelinating diseases of the central nervous system. In 2015, International Expert Panel established diagnostic criteria for NMOSD.
S. A. Dzhukkaeva   +3 more
doaj   +1 more source

A Review on Lactoferrin and Central Nervous System Diseases

open access: yesCells, 2021
Central nervous system (CNS) diseases are currently one of the major health issues around the world. Most CNS disorders are characterized by high oxidative stress levels and intense inflammatory responses in affected tissues.
Yu-qi Li, Chuang Guo
semanticscholar   +1 more source

Exosomes as cell-derivative carriers in the diagnosis and treatment of central nervous system diseases

open access: yesDrug Delivery and Translational Research, 2021
Exosomes are extracellular vesicles with the diameter ranging from 50 to 100 nm and are found in different body fluids such as blood, cerebrospinal fluid (CSF), urine and saliva. Like in case of various diseases, based on the parent cells, the content of
Gayatri Gopal Shetgaonkar   +5 more
semanticscholar   +1 more source

Facilitatory actions of guanidine on synaptic transmission in mammalian brain slices [PDF]

open access: yes, 1979
Guanidine administration may be beneficial in the treatment of amyotrophic lateral sclerosis and related diseases; however, the actions of guanidine on the mammalian central nervous system have not been investigated.
Galvan, Martin   +2 more
core   +1 more source

The Brain-Gut-Microbiome Axis. [PDF]

open access: yes, 2018
Preclinical and clinical studies have shown bidirectional interactions within the brain-gut-microbiome axis. Gut microbes communicate to the central nervous system through at least 3 parallel and interacting channels involving nervous, endocrine, and ...
Kalani, Amir   +3 more
core   +2 more sources

CRM1/XPO1 is associated with clinical outcome in glioma and represents a therapeutic target by perturbing multiple core pathways

open access: yesJournal of Hematology & Oncology, 2016
Background Malignant gliomas are associated with a high mortality rate, and effective treatment options are limited. Thus, the development of novel targeted treatments to battle this deadly disease is imperative.
Xuejiao Liu   +11 more
doaj   +1 more source

Anti-MOG associated myelitis

open access: yesНеврология, нейропсихиатрия, психосоматика, 2020
There is now increasing evidence that demyelinating disease with anti-myelin oligodendrocyte glycoprotein (anti-MOG) antibodies is an independent nosological unit.
A. I. Isaykin   +4 more
doaj   +1 more source

Advances in intranasal application of stem cells in the treatment of central nervous system diseases

open access: yesStem cell research & therapeutics, 2021
Stem cells are characterized by their self-renewal and multipotency and have great potential in the therapy of various disorders. However, the blood–brain barrier (BBB) limits the application of stem cells in the therapy of neurological disorders ...
Yu-ting Zhang   +5 more
semanticscholar   +1 more source

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