A Study of Qualitative Correlations Between Crucial Bio-markers and the Optimal Drug Regimen of Type-I Lepra Reaction: A Deterministic Approach [PDF]
Mycobacterium leprae is a bacteria that causes the disease Leprosy (Hansen's disease), which is a neglected tropical disease. More than 200000 cases are being reported per year world wide. This disease leads to a chronic stage known as Lepra reaction that majorly causes nerve damage of peripheral nervous system leading to loss of organs.
arxiv
Objective: to determine the sensitivity and specificity of method of determining the concentration of immunoglobulin free light chains (FLCs) in cerebrospinal fluid (CSF) in the diagnosis and differential diagnosis of multiple sclerosis (MS).Material and
Sh. R. Nabiev+8 more
doaj +1 more source
Old equations for a new system: A possible use of Navier-Stokes equations to model the circulation of spikes in the nervous system [PDF]
In the present work we discuss a possible application of Navier-Stokes-based models to the quantitative description of the circulation of nervous impulses throughout the nervous system. In previous works we have shown that the discharge from Basal Ganglia neurons from patients with Parkinson's disease share mathematical features with the velocity ...
arxiv
Regulation of Heart Beats by the Autonomous Nervous System in Health and Disease: Point-Process-Theory based Models and Simulation [V-I] [PDF]
We have advanced a point-process based framework for the regulation of heart beats by the autonomous nervous system and analyzed the model with and without feedback. The model without feedback was found amenable to several analytical results that help develop an intuition about the way the heart interacts with the nervous system.
arxiv
A reaction-diffusion model for the progression of Parkinson's disease [PDF]
The temporal and spatial development of Parkinson's disease has been characterised as the progressive formation of {\alpha}-synuclein aggregations through susceptible neuronal pathways. This article describes a new model for this progression mechanism in which Parkinsonian damage moves over time through the nervous system by the combined effect of the ...
arxiv
Introduction. Herniated intervertebral disc is a disease that is one of the main causes of sciatica and severe, sharp back pain and usually concerns adults aged 35 to 50 years. Aim.
Joanna Rosińczuk+3 more
doaj +1 more source
Full-field optical coherence tomography (FFOCT) can be used for the visualization of the myenteric plexus network and individual myenteric ganglia cells in situ, showing that FFOCT is a suitable method to image enteric nervous system activity.
Tony Durand+7 more
doaj +1 more source
Network Analyses and Nervous System Disorders [PDF]
Network analyses in nervous system disorders involves constructing and analyzing anatomical and functional brain networks from neuroimaging data to describe and predict the clinical syndromes that result from neuropathology. A network view of neurological disease and clinical syndromes facilitates accurate quantitative characterizations and ...
arxiv
Towards early diagnosis of Alzheimer's disease: Advances in immune-related blood biomarkers and computational modeling approaches [PDF]
Alzheimer's disease has an increasing prevalence in the population world-wide, yet current diagnostic methods based on recommended biomarkers are only available in specialized clinics. Due to these circumstances, Alzheimer's disease is usually diagnosed late, which contrasts with the currently available treatment options that are only effective for ...
arxiv
Research progress on adenosine in central nervous system diseases
As an endogenous neuroprotectant agent, adenosine is extensively distributed and is particularly abundant in the central nervous system (CNS). Under physiological conditions, the concentration of adenosine is low intra‐ and extracellularly, but increases
Yingjiao Liu+7 more
semanticscholar +1 more source