Results 81 to 90 of about 2,389,964 (125)

Overexpression of RASD1 inhibits glioma cell migration/invasion and inactivates the AKT/mTOR signaling pathway

open access: yesScientific Reports, 2017
The RAS signaling pathway is hyperactive in malignant glioma due to overexpression and/or increased activity. A previous study identified that RASD1, a member of the RAS superfamily of small G-proteins, is a significantly dysregulated gene in ...
Shangfeng Gao   +10 more
doaj   +1 more source

The central vein sign in the diagnosis of multiple sclerosis

open access: yesНеврология, нейропсихиатрия, психосоматика
Objective: to determine the specificity and sensitivity of the central vein sign (CVS) for the diagnosis of multiple sclerosis (MS). Material and methods. We analyzed 76 patients.
Sh. R. Nabiev   +3 more
doaj   +1 more source

Multiple Sclerosis disease: a computational approach for investigating its drug interactions [PDF]

open access: yesarXiv, 2020
Multiple Sclerosis (MS) is a chronic and potentially highly disabling disease that can cause permanent damage and deterioration of the central nervous system. In Europe it is the leading cause of non-traumatic disabilities in young adults, since more than 700,000 EU people suffer from MS. Although recent studies on MS pathophysiology have been provided,
arxiv  

Quality of Life and the Degree of Disease Acceptance In Patients with Spinocerebellar Ataxia

open access: yesPielęgniarstwo Neurologiczne i Neurochirurgiczne, 2018
Introduction. Spinocerebellar ataxias (SCA) belong to a group of rare genetic diseases. They are characterized by the multiplicity of symptoms, of which the most characteristic is limb ataxia and dysarthria.
Magdalena Kazimierska-Zając   +2 more
doaj   +1 more source

Risk Prediction of a Multiple Sclerosis Diagnosis [PDF]

open access: yesarXiv, 2013
Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. The progression and severity of MS varies by individual, but it is generally a disabling disease. Although medications have been developed to slow the disease progression and help manage symptoms, MS research has yet to result in a cure. Early diagnosis and
arxiv  

Extracellular vesicles in the diagnosis and treatment of central nervous system diseases

open access: yesNeural Regeneration Research, 2019
Extracellular vesicles, including exosomes and microvesicles, play a fundamental role in the activity of the nervous system, participating in signal transmission between neurons and providing the interaction of central nervous system with all body ...
A. Shaimardanova   +5 more
semanticscholar   +1 more source

Neuroprotective Effects of Anthraquinones from Rhubarb in Central Nervous System Diseases

open access: yesEvidence-Based Complementary and Alternative Medicine, 2019
Rhubarb is a well-known traditional Chinese medicine; it has been used in China for thousands of years. Rhubarb anthraquinones are the major medicinal ingredients derived from rhubarb including emodin, aloe-emodin, chrysophanol, rhein, physcion, and ...
Xun Li   +3 more
semanticscholar   +1 more source

Antioxidants and Nanotechnology: Promises and Limits of Potentially Disruptive Approaches in the Treatment of Central Nervous System Diseases

open access: yesAdvanced Healthcare Materials, 2019
Many central nervous system (CNS) diseases are still incurable and only symptomatic treatments are available. Oxidative stress is suggested to be a common hallmark, being able to cause and exacerbate the neuronal cell dysfunctions at the basis of these ...
C. Martinelli   +4 more
semanticscholar   +1 more source

High expression of Bruton’s tyrosine kinase (BTK) is required for EGFR-induced NF-κB activation and predicts poor prognosis in human glioma

open access: yesJournal of Experimental & Clinical Cancer Research, 2017
Background Malignant glioma is the most common primary brain tumor in adults and has a poor prognosis. However, there are no effective targeted therapies for glioma patients.
Chenglong Yue   +8 more
doaj   +1 more source

Automatic Chronic Degenerative Diseases Identification Using Enteric Nervous System Images [PDF]

open access: yesarXiv, 2020
Studies recently accomplished on the Enteric Nervous System have shown that chronic degenerative diseases affect the Enteric Glial Cells (EGC) and, thus, the development of recognition methods able to identify whether or not the EGC are affected by these type of diseases may be helpful in its diagnoses.
arxiv  

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