Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats
Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction
Einar Sjaastad Nordén +16 more
wiley +1 more source
An optimized one-tube, semi-nested PCR assay for Paracoccidioides brasiliensis detection
Introduction Herein, we report a one-tube, semi-nested-polymerase chain reaction (OTsn-PCR) assay for the detection of Paracoccidioides brasiliensis. Methods We developed the OTsn-PCR assay for the detection of P. brasiliensis in clinical specimens and
Amanda de Faveri Pitz +6 more
doaj +1 more source
Behavioral and epileptic phenotypes in a CHD2‐related developmental delay model
Abstract Objective Heterozygous loss‐of‐function mutations in the CHD2 gene, encoding chromodomain helicase DNA‐binding protein 2, are associated with severe childhood onset epilepsy, global developmental delay, and autistic features. Animal models that accurately recapitulate human phenotypes are crucial for understanding rare neurodevelopmental ...
Anat Mavashov +10 more
wiley +1 more source
Prevalence of canine coronavirus and parvovirus infections in dogs with gastroenteritis in Thailand
Canine coronavirus (CCV) and canine parvovirus type 2 (CPV-2) are the causative agents of gastroenteritis in dogs. Seventy fecal samples from dogs with signs of gastroenteritis (vomiting and diarrhea), twenty-five fecal samples from healthy dogs and one ...
K. Sakulwira +4 more
doaj +1 more source
Isolation and identification of caprine lentivirus in synovial fluid and blood using Nested PCR and western blotting. [PDF]
The caprine arthritis-encephalitis (CAE) is an infectious, multisystem disease, caused by a retrovirus belongs to the Lentivirus genus, which affects all ages goats and breed types. This study aimed to investigatethe caprine arthritis-encephalitis virus (
ALVES, F. S. F. +6 more
core
Herpes simplex keratitis: Challenges in diagnosis and clinical management [PDF]
Herpes simplex virus is responsible for numerous ocular diseases, the most common of which is herpetic stromal keratitis. This is a recurrent infection of the cornea that typically begins with a subclinical infection of the cornea that establishes a ...
Azher, Tayaba N +4 more
core +3 more sources
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer +11 more
wiley +1 more source
Nested Polymerase Chain Reaction (Nested-PCR) As A Diagnostic Technique for Intestinal Helminth Infection [PDF]
<p><em>Abstract</em> - <strong>Worm infections are still a health problem in the world, involving Indonesia. This disease generally rarely causes death, it has a detrimental impact on society such as malnutrition, anemia, productivity declining, and inhibits physical growth and intelligence in children.
openaire +1 more source
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li +10 more
wiley +1 more source
Promoter trapping in microalgae using the antibiotic paromomycin as selective agent [PDF]
The lack of highly active endogenous promoters to drive the expression of transgenes is one of the main drawbacks to achieving efficient transformation of many microalgal species.
Díaz Santos, Encarnación +5 more
core +3 more sources

