Results 91 to 100 of about 97,206 (312)

Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1304-1315, April 2025.
Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction
Einar Sjaastad Nordén   +16 more
wiley   +1 more source

An optimized one-tube, semi-nested PCR assay for Paracoccidioides brasiliensis detection

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2013
Introduction Herein, we report a one-tube, semi-nested-polymerase chain reaction (OTsn-PCR) assay for the detection of Paracoccidioides brasiliensis. Methods We developed the OTsn-PCR assay for the detection of P. brasiliensis in clinical specimens and
Amanda de Faveri Pitz   +6 more
doaj   +1 more source

Behavioral and epileptic phenotypes in a CHD2‐related developmental delay model

open access: yesEpilepsia, EarlyView.
Abstract Objective Heterozygous loss‐of‐function mutations in the CHD2 gene, encoding chromodomain helicase DNA‐binding protein 2, are associated with severe childhood onset epilepsy, global developmental delay, and autistic features. Animal models that accurately recapitulate human phenotypes are crucial for understanding rare neurodevelopmental ...
Anat Mavashov   +10 more
wiley   +1 more source

Prevalence of canine coronavirus and parvovirus infections in dogs with gastroenteritis in Thailand

open access: yesVeterinární Medicína, 2003
Canine coronavirus (CCV) and canine parvovirus type 2 (CPV-2) are the causative agents of gastroenteritis in dogs. Seventy fecal samples from dogs with signs of gastroenteritis (vomiting and diarrhea), twenty-five fecal samples from healthy dogs and one ...
K. Sakulwira   +4 more
doaj   +1 more source

Isolation and identification of caprine lentivirus in synovial fluid and blood using Nested PCR and western blotting. [PDF]

open access: yes, 2019
The caprine arthritis-encephalitis (CAE) is an infectious, multisystem disease, caused by a retrovirus belongs to the Lentivirus genus, which affects all ages goats and breed types. This study aimed to investigatethe caprine arthritis-encephalitis virus (
ALVES, F. S. F.   +6 more
core  

Herpes simplex keratitis: Challenges in diagnosis and clinical management [PDF]

open access: yes, 2017
Herpes simplex virus is responsible for numerous ocular diseases, the most common of which is herpetic stromal keratitis. This is a recurrent infection of the cornea that typically begins with a subclinical infection of the cornea that establishes a ...
Azher, Tayaba N   +4 more
core   +3 more sources

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer   +11 more
wiley   +1 more source

Nested Polymerase Chain Reaction (Nested-PCR) As A Diagnostic Technique for Intestinal Helminth Infection [PDF]

open access: yesJURNAL Al-AZHAR INDONESIA SERI SAINS DAN TEKNOLOGI, 2020
<p><em>Abstract</em> - <strong>Worm infections are still a health problem in the world, involving Indonesia. This disease generally rarely causes death, it has a detrimental impact on society such as malnutrition, anemia, productivity declining, and inhibits physical growth and intelligence in children.
openaire   +1 more source

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

open access: yesInterdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li   +10 more
wiley   +1 more source

Promoter trapping in microalgae using the antibiotic paromomycin as selective agent [PDF]

open access: yes, 2012
The lack of highly active endogenous promoters to drive the expression of transgenes is one of the main drawbacks to achieving efficient transformation of many microalgal species.
Díaz Santos, Encarnación   +5 more
core   +3 more sources

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