Results 191 to 200 of about 5,584,318 (357)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Nanoscale Mapping Reveals Periodic Organization of Neutrophil Extracellular Trap Proteins. [PDF]

Nano Lett
Winkler M, Mack TGA, Eickholt BJ, Schmoranzer J, Burn GL, Gimber N.   +5 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Semantic segmentation of light-toned veins in multimodal ChemCam data. [PDF]

Sci Rep
Lomashvili A, Rammelkamp K, Bhattacharjee P, Gasnault O, Clavé E, Egerland CH, Schröder S, Gabriel TSJ, Essunfeld A, Le Mouélic S, Demir B.   +10 more
europepmc   +1 more source

The Role of Renewable Energy to Achieve Net Zero Emissions: A Cost-Benefit Analysis of Indonesia's Power Sector Transition

Ira Fitriana, Hadiyanto Hadiyanto, Budi Warsito, Edi Hilmawan, Joko Santosa, Agus Sugiyono   +5 more
openalex   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

A deep learning algorithm for automatic 3D segmentation and classification of the sheep placenta in magnetic resonance images. [PDF]

Physiol Rep
Flouri D, Adamides G, Darby JRT, Holman SL, Panayides AS, David AL, Vavourakis V, Morrison JL, Melbourne A.   +8 more
europepmc   +1 more source

Nutritional and Contaminant Composition of Salmon Raised in Open Net Pens Compared to Land-Based Recirculating Aquaculture Systems and Wild Salmon

Stefanie M. Colombo, Jessica Carr, Carole‐Anne Gillis   +2 more
openalex   +1 more source

Potential of clean liquid fuels in decarbonizing transportation – An overlooked net- zero pathway?

, 2023
Md Zafar Ali Khan, Haider Ali Khan, Sai Sudharshan Ravi, James Turner, Muhammad Aziz   +4 more
openalex   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source