Results 31 to 40 of about 80,828 (221)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Characterization of Geochemical Disposal on Indicate and Mitigation Acid Mine Drainage at Coal Mining South Sumatera Indonesia

, 2014
Acid mine drainage (AMD) is a term U.S. used to describe command infiltration of acid surface water in the mining areas.The study of process for formation acid mine drainage can't be approached by two methods, the static and kinetic test. In the static
M. Said, M. Said; Polytecnic of Sriwijaya Palembang, Indonesia, PKS, A. Halim; Polytecnic of Sriwijaya Palembang, Indonesia, Wiwik DH, Endang; University of Sriwijaya Palembang, Indonesia, Syarif, Aida; Polytecnic of Sriwijaya Palembang, Indonesia   +3 more
core   +1 more source

Compartmentation of glycogen metabolism revealed from 13C isotopologue distributions [PDF]

, 2011
Background: Stable isotope tracers are used to assess metabolic flux profiles in living cells. The existing methods of measurement average out the isotopic isomer distribution in metabolites throughout the cell, whereas the knowledge of compartmental ...
Marin, Silvia, Loranne Agius, Selivanov, Vitaly, Marta Cascante, Roca Elias, Josep, Oresic, Matej, Cascante i Serratosa, Marta, Cascante, Marta, Igor Marin de Mas, Josep Roca, Marín Martínez, Silvia, Selivanov, Vitaly A., de Mas, Igor Marin, Silvia Marin, Agius, Loranne, Vitaly A Selivanov, Matej Orešič, Marín de Mas, Igor Bartolomé, Roca, Josep   +18 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

An integrated approach to AMD mitigation through sulfide removal from tailings

, 2010
Includes bibliographical references (leaves 67-73).The formation of acid mine drainage (AMD) from the microbial oxidation of sulfides in mineral waste deposits is one of the major challenges facing the mining industry worldwide.
Hesketh, Alexander H
core  

Overburden Geochemistry and Acid Rock Drainage Scale-Up Investigations at the Grasberg Mine, Papua Province, Indonesia

, 2003
The Grasberg is a large copper and gold open pit mine operated by PT Freeport Indonesia and located in the high equatorial mountains of Papua Province, Indonesia. The climate is alpine/sub-alpine with little seasonal variation in temperature and rainfall.
Miller, S., Richards, D., Andrina, J.
core   +1 more source

Correlation of degree of EVA crosslinking with formation and discharge of acetic acid in PV modules [PDF]

, 2017
Ethylene vinyl-acetate (EVA) encapsulated crystalline silicon PV modules see encapsulant related degradation such as the hydrolysis of EVA which leads to generation of acetic acid that corrodes cells and cell metallisation. The formation and discharge of
Jiang Zhu (1253214), Tom Betts (1258395), Ralph Gottschalg (1247661), Daniel Montiel-Chicharro (7208729)   +3 more
core   +1 more source