Results 41 to 50 of about 81,190 (221)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Acid Base Accounting of Mine Waste [PDF]

, 2014
There has been a growing demand for environmental assessment of a mining site in the recent years. It has become very important that field and laboratory tests are to be performed to study the overburden and resulting mine tailings characteristics.
Singh, Indrajeet, Nag, Rahul Anand
core  

Compartmentation of glycogen metabolism revealed from 13C isotopologue distributions [PDF]

, 2011
Background: Stable isotope tracers are used to assess metabolic flux profiles in living cells. The existing methods of measurement average out the isotopic isomer distribution in metabolites throughout the cell, whereas the knowledge of compartmental ...
Marin, Silvia, Loranne Agius, Selivanov, Vitaly, Marta Cascante, Roca Elias, Josep, Oresic, Matej, Cascante i Serratosa, Marta, Cascante, Marta, Igor Marin de Mas, Josep Roca, Marín Martínez, Silvia, Selivanov, Vitaly A., de Mas, Igor Marin, Silvia Marin, Agius, Loranne, Vitaly A Selivanov, Matej Orešič, Marín de Mas, Igor Bartolomé, Roca, Josep   +18 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Investigation into the sustainable use of mine waste to treat or prevent acid mine drainage [PDF]

, 2023
MEng (Chemical Engineering), North-West University, Potchefstroom CampusMine waste rock or tailings generate acid when sulphide minerals such as Pyrite (FeS2) oxidise in the presents of oxygen and water.
Van Wyk, Naythan
core   +1 more source

Correlation of degree of EVA crosslinking with formation and discharge of acetic acid in PV modules [PDF]

, 2017
Ethylene vinyl-acetate (EVA) encapsulated crystalline silicon PV modules see encapsulant related degradation such as the hydrolysis of EVA which leads to generation of acetic acid that corrodes cells and cell metallisation. The formation and discharge of
Jiang Zhu (1253214), Tom Betts (1258395), Ralph Gottschalg (1247661), Daniel Montiel-Chicharro (7208729)   +3 more
core   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

A mineralogical approach to evaluating laboratory scale acid rock drainage characterisation tests [PDF]

, 2016
Effective management of the risks associated with acid rock drainage (ARD) requires the ability to identify material with a potential to generate ARD reliably.
Franzidis, J-P, Harrison, S T L, Broadhurst, J L, Dyantyi, N, Becker, M   +4 more
core  

Nitrogen sorption as a tool for the characterisation of polysaccharide aerogels [PDF]

, 2011
Supercritically dried aerogels of several polysaccharides (chitin, chitosan, alginate, alginic acid, k- carrageenan, and agar) have been characterised by physisorption ofN2. Surface areas as high as 570m2 g−1 have been measured.
Tourrette, Audrey, M. Boissière, M. Robitzer, Valentin, Romain, R. Valentin, Horga, R., Horga, Ron, R. Horga, Boissière, Michel, Robitzer, Mike, Boissière, M., A. Tourrette, Quignard, Françoise, Valentin, R., Tourrette, A., Devoisselle, J.M., F. Quignard, Di Renzo, Francesco, J.M. Devoisselle, F. Di Renzo, Robitzer, M., Devoisselle, Jean-Marie, Quignard, F.   +22 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source