Results 61 to 70 of about 2,703,669 (301)

Uncertainty of net present value calculations and the impact on applying integrated maintenance approaches to the UK rail industry [PDF]

open access: yes, 2015
The Public performance indicator (PPI) is an important Key Performance Indicator for Network Rail and monitored carefully by the organisation and their external stakeholders.
Andrew, Starr   +3 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Managing the Balance Between Project Value and Net Present Value Using Reinforcement Learning

open access: yesIEEE Access
Project managers make decisions weighing financial returns (net present value, NPV) and value creation expected by stakeholders. Often, plans maximizing NPV neglect stakeholder benefits while those focused strictly on value creation may reduce financial ...
Claudio Szwarcfiter, Yale T. Herer
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

INVESTMENT APPRAISAL CRITERIA UNDERLYING INVESTMENT DECISIONS [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2011
Companies that want to grow their activity must decide on which investment projects to focus. Investment in financial terms, represents a use of capital that at the end of the investment wants to obtain a profitability. Following the investment, the
Căruntu Roxana Corina
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Valuation of Cryptocurrency Mining Operations

open access: yesLedger, 2018
Traditionally, the Net Present Value method has been used to compare diverging investment strategies. However, valuating crypto-projects with fiat-based currency is confusing due to extreme coin appreciation rates as compared to fiat interest rates. Here,
Jose Berengueres
doaj   +1 more source

The Net Present Value in Dynamic Models of the Firm [PDF]

open access: yes, 1989
The aim of this chapter is to introduce the net present value in dynamic models of the firm as a method to determine an optimal investment policy of the firm. In fact we show that it is optimal for the firm to grow at its maximum if the net present value of marginal investment is positive.
openaire   +6 more sources

Theoretical Analysis of Net Present Value

open access: yesBCP Business & Management, 2022
This paper reviews researches on net present value done by researchers in the past 25 years to summarize the research results and put forward limitations. Although the investment decision guided by net present value possesses a long history and investors use it widely in the current financial market, the author believes that it still has the value of ...
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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