Clostridium perfringens delta toxin is sequence related to beta toxin, NetB, and Staphylococcus pore-forming toxins, but shows functional differences. [PDF]
PLoS ONE, 2008 Clostridium perfringens produces numerous toxins, which are responsible for severe diseases in man and animals. Delta toxin is one of the three hemolysins released by a number of C. perfringens type C and possibly type B strains.
Maria Manich +7 more
doaj +6 more sources
The cytotoxicity and molecular mechanisms of the Clostridium perfringens NetB toxin [PDF]
Journal of Veterinary Medical Science, 2021 The necrotic enteritis toxin B-like (NetB) toxin secreted by Clostridium perfringens is a key virulence agent in the pathogenesis of avian necrotic enteritis, a disease that causes significant economic loss to the poultry industry worldwide. NetB was purified from Clostridium perfringens type G (CNEOP004) that was isolated from chickens with necrotic ...
Masafumi Mukamoto
exaly +5 more sources
Association between avian necrotic enteritis and Clostridium perfringens strains expressing NetB toxin. [PDF]
Vet Res, 2010 A novel toxin, NetB, has recently been identified in virulent avian Clostridium perfringens isolates and shown to be an essential virulence factor in a clinical necrotic enteritis isolate.
Keyburn AL +5 more
europepmc +6 more sources
The VirSR two-component signal transduction system regulates NetB toxin production in Clostridium perfringens. [PDF]
Infect Immun, 2010 Clostridium perfringens causes several diseases in domestic livestock, including necrotic enteritis in chickens, which is of concern to the poultry industry due to its health implications and associated economic cost. The novel pore-forming toxin NetB is
Cheung JK +6 more
europepmc +5 more sources
NetB Toxin and Immunization Against Necrotic Enteritis in Poultry: A Comprehensive Review [PDF]
Poultry Science Journal, 2023 Necrotic enteritis, caused by avian-specific NetB toxin-producing strains of Clostridium perfringens type A, has gained worldwide concerns due to increased production losses and mortality in broilers, increased veterinarian costs, and the chance of ...
Lida Abdolmohammadi Khiav +2 more
doaj +2 more sources
COMPARATIVE PCR AND ELISA FOR DETECTION OF ALPHA TOXIN AND NETB TOXIN GENES AND THEIR ANTIBODIES FROM CLOSTRIDIUM PERFRINGENSIN BROILER FARMS [PDF]
Assiut Veterinary Medical JournalClostridium perfringens is a spore-forming, anaerobic, Gram-positive bacterium that causes diseases in broilers. Necrotic enteritis toxins B (NetB) and alpha produced by Clostridium perfringens type A are etiologic agents of necrotic enteritis. The study
NAWAR JASIM +4 more
doaj +2 more sources
vaccination using profilin and NetB proteins in Montanide IMS adjuvant increases protective immunity against experimentally-induced necrotic enteritis [PDF]
Asian-Australasian Journal of Animal Sciences, 2017 Objective The effects of vaccinating 18-day-old chicken embryos with the combination of recombinant Eimeria profilin plus Clostridium perfringens (C.
Hyun Soon Lillehoj +7 more
doaj +2 more sources
Role of Clostridium perfringens Necrotic Enteritis B-like Toxin in Disease Pathogenesis
Vaccines, 2021 Necrotic enteritis (NE) is a devastating enteric disease caused by Clostridium perfringens type A/G that impacts the global poultry industry by compromising the performance, health, and welfare of chickens.
Kyung-Woo Lee, Hyun S. Lillehoj
doaj +2 more sources
Structural Insights into Clostridium perfringens Delta Toxin Pore Formation. [PDF]
PLoS ONE, 2013 Clostridium perfringens Delta toxin is one of the three hemolysin-like proteins produced by C. perfringens type C and possibly type B strains. One of the others, NetB, has been shown to be the major cause of Avian Nectrotic Enteritis, which following the
Jessica Huyet +5 more
doaj +2 more sources
Poultry Science, 2021 : Necrotic enteritis (NE) is a devastating enteric disease caused by Clostridium perfringens type G. One of the pore-forming toxins, NE B-like (NetB) toxin, secreted by pathogenic C. perfringens type G, has been proposed to be the main virulent factor in
Kyung-Woo Lee +6 more
doaj +2 more sources