Diffusion of Clostridium perfringens NetB positive strains in healthy and diseased chickens
For over 30 years α toxin was considered the key virulence factor responsible for the appearance of necrotic enteritis (NE) in chickens but, recently, a new toxin related to the occurrence of NE, called NetB, has been described.
Luca Bano +6 more
doaj +2 more sources
Variable protection against experimental broiler necrotic enteritis after immunisation with the C-terminal fragment of Clostridium perfringens alpha-toxin and a non-toxic NetB variant [PDF]
Necrotic enteritis toxin B (NetB) is a pore-forming toxin produced by Clostridium perfringens and has been shown to play a key role in avian necrotic enteritis (NE), a disease causing significant costs to the poultry production industry worldwide.
Geeraerts, S +15 more
core +6 more sources
Use of a Multiplex PCR for the Detection of Toxin‐Encoding Genes netB and tpeL in Strains of Clostridium perfringens [PDF]
Some studies have shown that the NetB toxin may be an important virulence factor of Clostridium perfringens associated necrotic enteritis in poultry. Additionally, research has shown that strains of C. perfringens positive for both the netB gene and a second toxin‐encoding gene, tpeL, appear to be more virulent than strains with only netB. In the past,
Matthew A. Bailey +4 more
wiley +3 more sources
The overall objective of this thesis was to develop a structural and functional understanding of NetB toxin from chicken necrotic enteritis isolate of Clostridium perfringens. The thesis contains a literature review, three published papers presenting the
Yan, Xuxia (3759469)
core +2 more sources
Isolation, toxin gene profiling, and phylogenetic analysis of Clostridium perfringens in Egyptian fruit bats: public health and epidemiological implications [PDF]
Clostridium perfringens (C. perfringens) is spore forming, toxin producing bacterium causing serious diseases in both animals and man and its presence in bats, especially the Egyptian fruit bat, are ecologically important yet increasingly interact with ...
Toka A. Allam +2 more
doaj +2 more sources
Lactobacillus-vectored nanobodies improve broiler productivity under sub-clinical necrotic enteritis with associated microbiome and transcriptome changes [PDF]
Sub-Clinical Necrotic Enteritis (SCNE), caused by toxin-producing Clostridium perfringens, is a major challenge in poultry production. SCNE has traditionally been managed with in-feed antibiotics; however, increasing concerns about the spread of ...
Ashley N. Hall +10 more
doaj +2 more sources
Antimicrobial susceptibility profiles of commensal Clostridium perfringens isolates from chickens in Hungarian poultry farms between 2022 and 2023 [PDF]
IntroductionOne of the most pressing challenges of our time is the global spread of antimicrobial resistance (AMR). Regular surveillance studies are critical for advancing collaborative efforts between animal and public health sectors, aligning with the ...
Ádám Kerek +9 more
doaj +2 more sources
Antimicrobial Susceptibility and Toxin Gene Profiles of Commensal Clostridium perfringens Isolates from Turkeys in Hungarian Poultry Farms (2022–2023) [PDF]
Background: The global spread of antimicrobial resistance (AMR) remains one of the greatest challenges of our time, necessitating collaboration among professionals in both the animal and public health sectors. One bacterial species that is developing AMR
Ádám Kerek +5 more
doaj +2 more sources
A novel Bacillus subtilis strain alleviates necrotic enteritis in chickens by reducing NetB toxin from Clostridium perfringens. [PDF]
Dayem SB +8 more
europepmc +2 more sources
Vaccination with recombinant NetB toxin partially protects broiler chickens from necrotic enteritis. [PDF]
NetB toxin from Clostridium perfringens is a major virulence factor in necrotic enteritis in poultry. In this study the efficacy of NetB as a vaccine antigen to protect chickens from necrotic enteritis was examined. Broiler chickens were immunized subcutaneously with purified recombinant NetB (rNetB), formalin treated bacterin and cell free toxoid with
Keyburn AL +7 more
europepmc +4 more sources

