Results 121 to 130 of about 19,431 (234)
Post-Translational Modifications in NETosis and NETs-Mediated Diseases
Biomolecules, 2019 Neutrophils undergo a unique form of cell death that generates neutrophil extracellular traps (NETs) that may help to neutralize invading pathogens and restore homeostasis.
Hussein J. Hamam, Nades Palaniyar
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Loss of testosterone impairs anti-tumor neutrophil function. [PDF]
, 2020 In men, the incidence of melanoma rises rapidly after age 50, and nearly two thirds of melanoma deaths are male. The immune system is known to play a key role in controlling the growth and spread of malignancies, but whether age- and sex-dependent ...
Arditi, Moshe +9 more
core +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Periodontology 2000, EarlyView.Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
, 2020 Autoimmune and autoinflammatory diseases have dramatically increased in both developed and developing countries. The etiology of these diseases is complex and developed due to multifactorial causes. It is tought that autoantigens are the basis of systemic autoimmune diseases in organism.
Sürsal, Neslihan, Yıldız, Kader
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Experimental Physiology, EarlyView.Abstract Circulating cell‐free DNA (cfDNA), circulating tumour DNA (ctDNA) and inflammatory cytokines have prognostic and predictive value in oncology. However, the effects of acute exercise on cfDNA levels are unknown. Here, we explore the kinetics of cfDNA, ctDNA and cytokines upon an incremental exercise test in a pilot cohort of cancer patients ...
Elmo W. I. Neuberger +10 more
wiley +1 more source
Auto-amplification and spatial propagation of neutrophil extracellular traps
Communications BiologyThe release of cellular DNA as neutrophil extracellular traps (NETs) plays a pivotal role in the immune response to pathogens by physically entrapping and killing microbes.
Pan Deng +5 more
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NET and NETosis – new phenomenon in immunology
Postępy Higieny i Medycyny Doświadczalnej, 2012 Neutrophils are one of the first cells of the immune system recruited to the site of infection, representing the host's most effective and numerous front-line defenders. Recently, a novel antimicrobial mechanism of neutrophils has been described: upon activation, they release DNA and a subset of their granule content, forming neutrophil extracellular ...
Natalia, Matoszka +3 more
openaire +2 more sources
International Journal of Cancer, Volume 158, Issue 10, Page 2771-2783, 15 May 2026.What's New? Circulating nuclear DNA (cir‐nDNA)‐based assessment of minimal residual disease (MRD) offers powerful post‐surgery prognostic insight for stage III colon cancer (CC). Sparse knowledge of post‐surgical variations and origins in cir‐nDNA, however, has limited its clinical application.
Andrei Kudriavtsev +17 more
wiley +1 more source
Piezo1 expression in neutrophils regulates shear-induced NETosis
Nature CommunicationsNeutrophil infiltration and subsequent extracellular trap formation (NETosis) is a contributing factor in sterile inflammation. Furthermore, neutrophil extracellular traps (NETs) are prothrombotic, as they provide a scaffold for platelets and red blood ...
Sara Baratchi +9 more
doaj +1 more source
Advanced Science, Volume 13, Issue 19, 2 April 2026.We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu +8 more
wiley +1 more source