Results 201 to 210 of about 104,683 (267)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Neutrophil extracellular traps in the tumor microenvironment, metastasis, therapy, and beyond: advances, challenges, and perspectives. [PDF]

J Hematol Oncol
He J, Zhou Z, Cheng G, Li H, Tu J, Fan Z, Qiu X, Chen W, Chen Y, Li L, Li C, Li Z, Chen L, Lu Q.   +13 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Impact of Insecticide-Treated Nets on <i>Plasmodium falciparum</i> Infection Rates: A Meta-Analysis. [PDF]

Trop Med Infect Dis
Karaca Biçakçi N, Çalmaz A, Ayyildiz Akin M, Tan CS, Barasarathi J, Oyinloye BE, Umidjon A, Egamberdiyev K, Avazmetova I.   +8 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Tumor-Derived Exosomal Fatty Acids Reprogram Neutrophils to Drive Neutrophil Extracellular Traps Formation and Lung Cancer Progression. [PDF]

Research (Wash D C)
Han L, Chen Y, Wu R, Chen J, Chen Z, Cai Y, Huang S, Gu H, Zhuang X, Lv Y, Li H, Li L, Wang G.   +12 more
europepmc   +1 more source

Tidal Nets of the Solway

Scottish Studies, 1958
Werner Kissling
doaj  

Primary hepatic neuroendocrine tumor with multifocal liver involvement: A case report and review of the literature. [PDF]

Radiol Case Rep
Guennouni A, Essaber H, Bahha S, Laamrani FZ, Omor Y, Latib R, Amalik S, Aroudan Y, Salihon M, Kabbaj N.   +9 more
europepmc   +1 more source

Temporal transcriptomic profiling of pulmonary thromboembolism reveals persistent NETosis- and ferroptosis-associated gene signatures and enhanced thrombolysis with adjunctive DNase I. [PDF]

PLoS One
Chen J, Chao L, Han S, Jia Z, Chen W, Liu Z, Li J, Yan X.   +7 more
europepmc   +1 more source

Analysis of the efficacy and safety of endoscopic full-thickness resection in the treatment of rectal neuroendocrine tumors. [PDF]

Front Med (Lausanne)
Li L, Yin H, He A, Ye Y, Zhang Y.
europepmc   +1 more source