Results 51 to 60 of about 2,155,438 (269)
A Review of Visibility Graph Analysis
IEEE AccessA graph approach to time series data provides a new perspective for analyzing and comprehending the characteristics of the data. One common method of converting time series into a graph is through visibility graph analysis.
Hadis Azizi, Sadegh Sulaimany
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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International Journal of Ambient Computing and Intelligence, 2012 Social Network Analysis is attracting growing attention as social networking sites and their enabled applications transform and impact society. This paper aims to provide a comprehensive review of social network analysis state of the art research and practice.
Darren Quinn +2 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Hopelessness: A Network Analysis [PDF]
Cognitive Therapy and Research, 2018 Hopelessness is a complex phenomenon with important clinical consequences, such as depression and suicidality. Despite its major impact on mental health, little is known about the structure of hopelessness. In this study, hopelessness was investigated in a large community sample (n = 1985), recruited to be highly representative of general population in
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Three-Channel Convolutional Neural Network for Polarimetric SAR Images Classification
IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2020 Terrain classification is an important topic in polarimetric synthetic aperture radar (PolSAR) image processing and interpretation. A novel PolSAR classification method based on the three-channel convolutional neural network (Tc-CNN) is proposed and this
Wenqiang Hua, Wen Xie, Xiaomin Jin
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Smoothed analysis of balancing networks [PDF]
Random Structures & Algorithms, 2009 AbstractIn a balancing network each processor has an initial collection of unit‐size jobs (tokens) and in each round, pairs of processors connected by balancers split their load as evenly as possible. An excess token (if any) is placed according to some predefined rule. As it turns out, this rule crucially affects the performance of the network.
Tobias Friedrich 0001 +2 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source