Results 51 to 60 of about 166,926 (313)

Sample-Adaptive Classification Inference Network

open access: yesNeural Processing Letters, 2023
Abstract Existing pre-trained models have yielded promising results in terms of computational time reduction. However, these models only focus on pruning simple sentences or less salient words, while neglecting the treatment of relatively complex sentences. It is frequently these sentences that cause the loss of model accuracy.
Juan Yang   +3 more
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Inference of Causal Networks Using a Topological Threshold

open access: yesIEEE Access
We propose a constraint-based algorithm, which automatically determines causal relevance thresholds, to infer causal networks from data. We call these topological thresholds.
Filipe Barroso   +2 more
doaj   +1 more source

Identification of Boolean Network Models From Time Series Data Incorporating Prior Knowledge

open access: yesFrontiers in Physiology, 2018
Motivation: Mathematical models take an important place in science and engineering. A model can help scientists to explain dynamic behavior of a system and to understand the functionality of system components.
Thomas Leifeld, Zhihua Zhang, Ping Zhang
doaj   +1 more source

Inferring Centrality from Network Snapshots

open access: yesScientific Reports, 2017
AbstractThe topology and dynamics of a complex network shape its functionality. However, the topologies of many large-scale networks are either unavailable or incomplete. Without the explicit knowledge of network topology, we show how the data generated from the network dynamics can be utilised to infer the tempo centrality, which is proposed to ...
Haibin Shao   +3 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Harnessing Unsupervised Ensemble Learning for Biomedical Applications: A Review of Methods and Advances

open access: yesMathematics
Advancements in data availability and computational techniques, including machine learning, have transformed the field of bioinformatics, enabling the robust analysis of complex, high-dimensional, and heterogeneous biomedical data.
Mehmet Eren Ahsen
doaj   +1 more source

Applying causal discovery to single-cell analyses using CausalCell

open access: yeseLife, 2023
Correlation between objects is prone to occur coincidentally, and exploring correlation or association in most situations does not answer scientific questions rich in causality.
Yujian Wen   +7 more
doaj   +1 more source

Trace complexity of network inference [PDF]

open access: yesProceedings of the 19th ACM SIGKDD international conference on Knowledge discovery and data mining, 2013
25 pages, preliminary version appeared in Proceedings of the 19th ACM SIGKDD International Conference on Knowledge Discovery and Data Mining (KDD 2013)
Bruno Abrahao   +3 more
openaire   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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