Results 81 to 90 of about 7,468,732 (318)

Granger-Causality Inference of the Existence of Unobserved Important Components in Network Analysis

open access: yesEntropy, 2021
Detecting causal interrelationships in multivariate systems, in terms of the Granger-causality concept, is of major interest for applications in many fields. Analyzing all the relevant components of a system is almost impossible, which contrasts with the
Heba Elsegai
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Gene Regulatory Network Inference: Connecting Plant Biology and Mathematical Modeling

open access: yesFrontiers in Genetics, 2020
Plant responses to environmental and intrinsic signals are tightly controlled by multiple transcription factors (TFs). These TFs and their regulatory connections form gene regulatory networks (GRNs), which provide a blueprint of the transcriptional ...
Lisa Van den Broeck   +5 more
doaj   +1 more source

Neural Natural Language Inference Models Enhanced with External Knowledge

open access: yes, 2018
Modeling natural language inference is a very challenging task. With the availability of large annotated data, it has recently become feasible to train complex models such as neural-network-based inference models, which have shown to achieve the state-of-
Chen, Qian   +4 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

corto: a lightweight R package for Gene Network Inference and Master Regulator Analysis

open access: yesbioRxiv, 2020
Motivation Gene Network Inference and Master Regulator Analysis (MRA) have been widely adopted to define specific transcriptional perturbations from gene expression signatures.
D. Mercatelli   +2 more
semanticscholar   +1 more source

Prediction of Neighbor-Dependent Microbial Interactions From Limited Population Data

open access: yesFrontiers in Microbiology, 2020
Modulation of interspecies interactions by the presence of neighbor species is a key ecological factor that governs dynamics and function of microbial communities, yet the development of theoretical frameworks explicit for understanding context-dependent
Joon-Yong Lee   +11 more
doaj   +1 more source

Classifying pairs with trees for supervised biological network inference [PDF]

open access: yes, 2014
Networks are ubiquitous in biology and computational approaches have been largely investigated for their inference. In particular, supervised machine learning methods can be used to complete a partially known network by integrating various measurements ...
Babu, M. Madan   +3 more
core  

Sample-Adaptive Classification Inference Network

open access: yesNeural Processing Letters, 2023
Abstract Existing pre-trained models have yielded promising results in terms of computational time reduction. However, these models only focus on pruning simple sentences or less salient words, while neglecting the treatment of relatively complex sentences. It is frequently these sentences that cause the loss of model accuracy.
Juan Yang   +3 more
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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