Results 81 to 90 of about 7,014,814 (396)
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
Big Data Transforms Discovery-Utilization Therapeutics Continuum. [PDF]
, 2016 Enabling omic technologies adopt a holistic view to produce unprecedented insights into the molecular underpinnings of health and disease, in part, by generating massive high-dimensional biological data.
Alfirevic +17 more
core +2 more sources
Frontiers in Pharmacology, 2018 Lapses in the graft-vs.-host disease (GVHD) prophylaxis and side effects of current standard care following allogeneic hematopoietic stem cell transplantation (allo-HSCT) call for novel regimens.
Ming Lyu +17 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Danggui Shaoyao San (DSS), a well-known formula, has been successfully applied in treating primary dysmenorrhea (PD) in China. However, its material basis and mechanism are still unrevealed.
Hui Xiong +7 more
semanticscholar +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Pharmacological Effects of Agastache rugosa against Gastritis Using a Network Pharmacology Approach [PDF]
Biomolecules, 2020 Agastache rugosa is used as a Korean traditional medicine to treat gastric diseases. However, the active ingredients and pharmacological targets of A. rugosa are unknown. In this study, we aimed to reveal the pharmacological effects of A. rugosa on gastritis by combining a mice model and a network pharmacology method.
Hyeon-Hwa Nam +8 more
openaire +3 more sources
In the Flesh and the Gothic Pharmacology of Everyday Life; or Into and Out of the Gothic [PDF]
, 2016 One of the key questions facing Gothic Studies today is that of its migration into and out of its once familiar generic or symbolic modes of representation.
Murnane, Barry
core +1 more source
How pharmacoepidemiology networks can manage distributed analyses to improve replicability and transparency and minimize bias [PDF]
, 2020 Several pharmacoepidemiology networks have been developed over the past decade that use a distributed approach, implementing the same analysis at multiple data sites, to preserve privacy and minimize data sharing.
Brown, Jeffrey S. +5 more
core +2 more sources
Journal of Orthopaedic Surgery and Research, 2022 Background Diabetic osteoporosis (DOP) is one of the chronic complications of diabetes mellitus, but without a standardized treatment plan till now. Liuwei Dihuang pill (LDP) has gradually exerted a remarkable effect on DOP in recent years; its specific ...
Zhaoqi Lu +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source