Results 121 to 130 of about 271,086 (294)

BDNF and Lactate as Modulators of Hippocampal CA3 Network Physiology. [PDF]

Cell Mol Neurobiol, 2023
Griego E, Galván EJ.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Scientific Network of Surfactants: Structural Analysis [PDF]

, 2006
The scientific network of the surfactants and related subjects has been analyzed with the CoPalRed© knowledge system. The actors studied have been countries, research centers and laboratories, researchers, and journals.
Ruiz-Baños, Rosario, Rosario Ruiz‐Baños, Jurado-Alameda, Encarnación, Rafael Bailón‐Moreno, Bailón-Moreno, Rafael, Encarnación Jurado‐Alameda   +5 more
core   +1 more source

Mutual information-based teamwork evaluation in real-world environments: an exploratory investigation with professional surgeons

Frontiers in Network Physiology
PurposeTeamwork involves intricate interactions among individuals or groups with shared goals. It necessitates effective communication, defined roles, decision-making processes, and the allocation of cognitive and emotional resources.
Vincenzo Ronca, Vincenzo Ronca, Lidia Castagneto Gissey, Maria Irene Bellini, Alessandra Iodice, Pietro Aricò, Pietro Aricò, Gianluca Di Flumeri, Gianluca Di Flumeri, Andrea Giorgi, Andrea Giorgi, Alessia Vozzi, Alessia Vozzi, Rossella Capotorto, Stefano Bonelli, Laura Moens, Fabio Babiloni, Fabio Babiloni, Fabio Babiloni, Giovanni Casella, Gianluca Borghini, Gianluca Borghini   +21 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

An infrastructure for neural network construction

, 2005
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.After many years of research the area of Artificial Intelligence is still searching for ways to construct a truly intelligent system.
Stewart, Richard
core  

Mesenchyme Homeobox 2 Enhances Migration of Endothelial Colony Forming Cells Exposed to Intrauterine Diabetes Mellitus

, 2017
Diabetes mellitus (DM) during pregnancy has long-lasting implications for the fetus, including cardiovascular morbidity. Previously, we showed that endothelial colony forming cells (ECFCs) from DM human pregnancies have decreased vasculogenic potential ...
Emily K. Blue, BreAnn M. Sheehan, Blue, Emily K., Gohn, Cassandra R., Sheehan, BreAnn M., Haneline, Laura S., Kaela M. Varberg, Cassandra R. Gohn, Varberg, Kaela M., Laura S. Haneline   +9 more
core   +1 more source

Early parasympathetic dysfunction in Parkinson’s disease: insights from information-theoretic analysis

Frontiers in Network Physiology
IntroductionParasympathetic nervous system (PNS) dysfunction in Parkinson’s disease (PD) has been frequently evaluated using heart rate variability (HRV) analysis in the time and frequency domains. Findings across studies have been inconsistent, limiting
Jana Cernanova Krohova, Jana Oleksakova, Zuzana Turianikova, Barbora Czippelova, Milan Grofik, Egon Kurca, Michal Javorka   +6 more
doaj   +1 more source

Editorial: Network physiology, insights into the brain system: 2021. [PDF]

Front Netw Physiol, 2022
Lehnertz K.
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source