Results 131 to 140 of about 271,086 (294)

Oscillatory components of bidirectional cardio-respiratory coupling in depression and suicidal ideation: insights from swarm decomposition and entropy analysis

Frontiers in Network Physiology
IntroductionMajor depressive disorder (MDD) and MDD with suicidal ideation (MDDSI) present with heterogeneous symptoms, complicating diagnosis and treatment.
Herbert F. Jelinek, Herbert F. Jelinek, Mohanad Alkhodari, Mohanad Alkhodari, Ahsan H. Khandoker, Ahsan H. Khandoker, Leontios J. Hadjileontiadis, Leontios J. Hadjileontiadis   +7 more
doaj   +1 more source

Network Physiology of Exercise: Beyond Molecular and Omics Perspectives. [PDF]

Sports Med Open, 2022
Balagué N, Hristovski R, Almarcha M, Garcia-Retortillo S, Ivanov PC.   +4 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

IPA gene network analysis: Top differentially regulated genes at day 21 and day 28 associated with mammary gland (patho-)physiology.

, 2014
IPA gene network analysis: Top differentially regulated genes at day 21 and day 28 associated with mammary gland (patho-)physiology.
Helmuth G. Doerr (582178), Ilona Winterfeld (582175), Andrea Hartner (299642), Fabian B. Fahlbusch (282236), Lea Beinder (582173), Carlos Menendez-Castro (299643), Matthias Ruebner (282231), Rainer Wachtveitl (350490), Nina Faehrmann (582174), Stephanie C. Noegel (582177), Hanna Huebner (582176), Wolfgang Rascher (299647), Manfred Rauh (548819)   +12 more
core   +1 more source

Analysis of a model for bacteriophage infections and bacteria defense: a synergetics perspective

Frontiers in Network Physiology
A model for bacteriophage infections and bacteria defense is analyzed using the concepts of synergetics. The model order parameter is determined and the corresponding amplitude equations are derived.
T. D. Frank, T. D. Frank
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Metamodulation of a spinal locomotor network by nitric oxide

, 2010
Flexibility in the output of spinal networks can be accomplished by the actions of neuromodulators; however, little is known about how the process of neuromodulation itself may be modulated.
Sillar, Keith Thomas, McLean, DL
core   +1 more source

Machine learning-driven exploration of therapeutic targets for atrial fibrillation-joint analysis of single-cell and bulk transcriptomes and experimental validation

Frontiers in Cardiovascular Medicine
BackgroundTo explore new therapeutic targets and strategies for atrial fibrillation (AF) by analyzing gene expression profiles of AF patients using machine learning techniques combined with transcriptomic data, and to uncover the potential molecular ...
Yicheng Wang, Yicheng Wang, Yicheng Wang, Hong-Yi Yang, Hong-Yi Yang, Hong-Yi Yang, Zi-Ao Fan, Zi-Ao Fan, Zi-Ao Fan, Jian-Cheng Zhang, Jian-Cheng Zhang, Jian-Cheng Zhang   +11 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Quantifying coupling and causality in dynamic bivariate systems: a unified framework for time-domain, spectral, and information-theoretic analysis

Frontiers in Network Physiology
Understanding the underlying dynamics of complex real-world systems, such as neurophysiological and climate systems, requires quantifying the functional interactions between the system units under different scenarios.
Laura Sparacino, Helder Pinto, Chiara Barà, Yuri Antonacci, Riccardo Pernice, Ana Paula Rocha, Luca Faes, Luca Faes   +7 more
doaj   +1 more source