Results 141 to 150 of about 271,086 (294)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Applications of synergetics in psychology: interpersonal synchrony in social systems

open access: yesFrontiers in Network Physiology
The Haken-Kelso-Bunz paradigm of motor coordination has instigated experimental research on pattern formation with a focus on body movement in intra- as well as interpersonal contexts.
Wolfgang Tschacher
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Reticulate eruptions. Part 1: Vascular networks and physiology

open access: yes, 2011
Reticulate pattern is one of the most important dermatological signs of a pathological process involving the superficial vascular networks. Vascular malformations, such as cutis marmorata congenita telangiectasia and benign forms of livedo reticularis ...
Parsi, Kurosh   +11 more
core   +1 more source

Signal propagation in small networks of Hodgkin-Huxley neurons

open access: yesFrontiers in Network Physiology
The study of neuron models and their networks is a riveting topic for many researchers worldwide because it allows to glimpse the fundamental processes using accessible methodology. The paper considers dynamics of small networks of Hodkin-Huxley neurons,
Tatiana R. Bogatenko   +2 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Self-organization and circular causation as synergetic foundations of social interaction: a multilayer network perspective

open access: yesFrontiers in Network Physiology
Social interaction emerges from complex, dynamic couplings among neural, physiological, and behavioral subsystems across individuals. Here, we propose the Synergetic Multilayer Social Interaction Hypothesis, which frames interpersonal coordination as a ...
Viktor Müller
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Assessing effects of vibroacoustic stimulation compared to a guided mindfulness meditation using the biosignal of human speech

open access: yesFrontiers in Network Physiology
IntroductionHigh stress and low wellbeing pose severe individual, societal and economic threats, and there is a pressing demand for non-invasive stress reduction tools.
Charlotte Fooks, Oliver Niebuhr
doaj   +1 more source

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