Results 91 to 100 of about 2,970,315 (253)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Rapid 3D printing of hierarchical nanoporous copper structures with self-disintegration capability
Nature CommunicationsMicro-architected nanoporous metals are widely used in electrochemical and catalytic systems, but conventional powder metallurgy cannot readily produce structurally complex, microscale variants.
Luyang Liu +10 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
RWA of hypercube communications embedded on a family of optical double-loop networks
, 2007 In this paper, we study routing and wavelength assignment (RWA) for realizing hypercube communications on a family of WDM optical double-loop networks, chordal rings of degree 4.
Hong Shen +3 more
core +1 more source
地震科学进展In this paper，the regional full waveform inversion using the broadband waveforms recorded by China Seismic Network were conducted，and the focal mechanism solutions of the 59 earthquakes with M≥4.0 occurred in the mainland of China during March to June ...
Shanshan Liang +4 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Networking Outside the Networks
, 2009 Due to the recent unfortunate events, for example, the ability to monitor and control the messages and data transferred in the Internet has gained attention. However, there also exist methods for networking beyond any control. Smart, hand-held mobile devices with support for communication technologies such as the WLAN allow spontaneous, ad-hoc networks
openaire +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Information & Networks : final prospectus report
, 2015 This final prospectus review of the Information and Networks (I&N) program serves to inform evaluators of IDRC’s progress in achieving goals set, 2011- 2016.
IDRC. Information and Networks Program
core