Results 111 to 120 of about 2,970,315 (253)
地震科学进展This article has summarized the shortcomings and deficiencies in the construction and operation of the earthquake monitoring station network of China, analyzes the trend of modernization development of the monitoring station network, and proposes ...
Dan Yu +4 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
, 2011 Guiding readers through the basics of these rapidly emerging networks to more advanced concepts and future expectations, Mobile Ad hoc Networks: Current Status and Future Trends identifies and examines the most pressing research issues in Mobile Ad hoc ...
Hamilton Ortiz, Jesús +2 more
core +1 more source
地震科学进展In this paper，the regional full waveform inversion using the broadband waveforms recorded by China Seismic Network were conducted, and the focal mechanism solutions of the 38 earthquakes with M≥4.0 occurred in the mainland of China during July to ...
Shanshan Liang +4 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Complexity, Governance and Networks: Introduction to the Inaugural Issue
, 2014 From the introduction: 1. Yet Another Journal? Why is it necessary to publish a new journal about complexity, governance, and networks? There has been an increasing interest in complexity, governance, and network studies in recent decades.
Morçöl, Göktuğ +2 more
core +1 more source
Dizhen xuebao鲁东—黄海地块西部为华北地块东侧的次级地块，其地震活动具有显著的周期特征，地块内部的中强地震活动特征和周边大震对该地区的影响对研究该地区地震活动状态有重要意义。采用小波分析方法定量计算了鲁东—黄海地块西部历史地震的活动周期，并结合中强地震活动的定性分析、时空演化、能量释放及周边大震等资料，探讨了该地区的地震活动特征。结果显示：① 鲁东—黄海地块西部M5.0以上地震活动存在着60.6—78.6 a的长周期，该周期反映了地震活跃—平静的韵律特征，据此M≥5.0地震可划分为活跃时段 Ⅰ （1844—1879年）
Mingxiao Li +6 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source