Results 101 to 110 of about 13,581,527 (336)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A Critical Appraisal of Remedies in the EU Microsoft Cases [PDF]
We discuss and compare the remedies in the two cases antitrust cases of the European Union (EU) against Microsoft. The first EU case alleged (i) that Microsoft illegally bundled the Windows Media Player (WMP) with Windows; and (ii) that Microsoft did not
Ioannis Lianos, Nicholas Economides
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Why Imposing New Tolls on Third-Party Content and Applications Threatens Innovation and Will Not Improve Broadband Providers’ Investment [PDF]
While some broadband providers have called Internet content and application providers free riders on their infrastructure, this is incorrect and misguided.
Nicholas Economides
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Dizhen xuebao, 2019 预测效果的科学评价是预测学科必须要解决的问题，对地震预测效果的评价一般分为两种，一种是对单次预测成败的评判，另一种是对方法或手段多次预测效果的统计评分。本文提出了针对单次有震预测是否准确的定量评价方法，即地震预测准确性A值评分法。针对我国地震预测现状，本文约定了准确性评分由预测与实际地震的对应情况（简称“对应度” ）和时、空、强预测窗口的精确程度（简称“精确度” ）综合决定，同时，还给出了对应度的计算方法和精确度的评价标准。通过对四川省地震局2013年2月上报的短期预测意见进行试算 ...
Wei Yan +6 more
doaj +1 more source
Cancer gene expression profiles associated with clinical outcomes to chemotherapy treatments
BMC Medical Genomics, 2020 Background Machine learning (ML) methods still have limited applicability in personalized oncology due to low numbers of available clinically annotated molecular profiles.
Nicolas Borisov +4 more
doaj +1 more source
Hit and Miss: Leverage, Sacrifice, and Refusal to Deal in the Supreme Court Decision in Trinko [PDF]
Under the rules of the Telecommunications Act of 1996, incumbent local exchange carriers, including Verizon, were obligated to lease parts of their local telecommunications network to any firm at “cost plus a reasonable profit” prices which could combine
Nicholas Economides
core
Network coding for non-uniform demands [PDF]
, 2005 Non-uniform demand networks are defined as a useful connection model, in between multicasts and general connections. In these networks, each sink demands a certain number of messages, without specifying their identities.
Bruck, Jehoshua, Cassuto, Yuval
core +3 more sources