Results 81 to 90 of about 13,581,527 (336)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Mundakkai-Chooralmala landslide: assessment of initiation, progression, and impact

Scientific Reports
Globally, the emergence of multi-hazard scenarios and cascaded disasters is significantly rising . During the 2024 monsoon in Wayanad District, Kerala, India, torrential rainfall triggered landslides, erosion, and flash floods, resulting in over 400 ...
Maneesha Vinodini Ramesh, Hari Chandana Ekkirala, Balmukund Singh, Nitin Kumar M, Sabari Ramesh, Aadityan Sridharan, Nirmala Vasudevan, Sudesh Kumar Wadhawan   +7 more
doaj   +1 more source

Greenways and Ecological Networks: Concepts, Differences, Similarities [PDF]

, 2017
In recent decades green infrastructure (GI) frameworks have been widely used for developing theoretical and practical models of sustainable land reorganization.
Balestrieri, Mara, Ganciu, Amedeo
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A possible characteristic of foreshocks derived from the evaluation of loading/unloading induced by earth tides

Frontiers in Earth Science, 2022
The detection of the potential of a larger event immediately after a moderate earthquake is a quite difficult problem. In this work, we devised an approach to determine whether an earthquake is a foreshock to a larger mainshock by evaluating loading ...
Huaizhong Yu, Jie Liu, Yawei Ma, Rui Yan, Chen Yu, Shengle Li, Zhigao Yang, Min Hong, Hongwei Tu, Zhiwei Zhang, Binbin Zhao, Yuchuan Ma   +11 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A self-evolution cyber attack scheme generation system for cybersecurity evaluation

Scientific Reports
With the increasing complexity of network attacks, defense systems face significant challenges in maintaining cybersecurity. To effectively evaluate and optimize defense strategies, this paper proposes a self-evolution attack scenario generation system ...
Mingsheng Yang, Yan Jia, Yangyang Mei, Jie Yang, Weihong Han, Jiawei Zhang, Zhuocheng Yu   +6 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

ShotFlex: A reinforcement learning-based cyber attack path generation method for cybersecurity evaluation

Security and Safety
Penetration testing is an important method for discovering hidden vulnerabilities and attack paths in network systems, which is of great significance for evaluating network security.
Yu Zhuocheng, Jia Yan, Han WeiHong, Zhang Jiawei, Yang Mingsheng, Mei Yangyang   +5 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source