Results 131 to 140 of about 337,560 (313)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
, 2013 Key to the faculty and students in the 2013 Neural Systems and Biology course at the Marine Biological Laboratory in Woods Hole ...
Kleindinst, Thomas N
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On impulsive autoassociative neural networks
, 2000 Many systems existing in physics, chemistry, biology, engineering, and information science can be characterized by impulsive dynamics caused by abrupt jumps at certain instants during the process.
Guanrong Chen +5 more
core +1 more source
Implentation of neural networks in biology and biomedicine
, 2023 Umjetne neuralne mreže su računalni sustavi koji su inspirirani biološkim neuronskim mrežama. Ovi sustavi su međusobno povezane mreže čvorova (“neuroni”) koji rade zajedno kako bi proizveli izlaznu funkciju.
Hlaj, Ivona
core +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Neural cellular automata: Applications to biology and beyond classical AI
Physics of Life ReviewsNeural Cellular Automata (NCA) represent a powerful framework for modeling biological self-organization, extending classical rule-based systems with trainable, differentiable (or evolvable) update rules that capture the adaptive self-regulatory dynamics of living matter.
Benedikt Hartl +2 more
openaire +3 more sources
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
SPINS - um simulador neural para visualização de aspectos de aprendizado utilizando neurônios spiking [PDF]
, 2005 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Ciência da Computação.Os artefatos inteligentes podem ser considerados mecanismos inspirados biologicamente.
Sousa, Giseli de
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Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source