Results 121 to 130 of about 337,560 (313)
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Isolation, Induction of Neural and Glial Differentiation and Evaluating the Expression of Five Self Renewal Genes in Adult Mouse Neural Stem Cells [PDF]
Purpose: Isolation, induction of neural and glial differentiation and evaluating the expression of Nucleostemin, ZFX, Hoxb-4, Sox-9 & Bmi-1 self renewal genes in adult mouse neural stem cells Materials and Methods: Breifly, for isolation of neural stem
مولا, سید جواد +6 more
core
Information and the function of neurons [PDF]
, 2011 Many of us consider it uncontroversial that information processing is a natural function of the brain. Since functions in biology are only won through empirical investigation, there should be a significant body of unambiguous evidence that supports this
Burock, Marc
core
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Caracterização e expansão in vitro de células tronco epidermais derivadas da crista neural [PDF]
, 2013 TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.A implementação de tecnologias baseadas no uso de células tronco adultas requer a identificação de fontes prontamente disponíveis bem como o estabelecimento ...
Bressan, Raul Bardini
core
CellsParkinson’s disease (PD) is characterized by degeneration of nigrostriatal dopaminergic neurons (DNs) and movement disorders. Low efficiency of pharmacotherapy requires improvement, e.g., using receptor agonists or antagonists as drugs.
Dmitry Troshev +3 more
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Medical imaging analysis with artificial neural networks
, 2010 Given that neural networks have been widely reported in the research community of medical imaging, we provide a focused literature survey on recent neural network developments in computer-aided diagnosis, medical image segmentation and edge detection ...
J. Ren +8 more
core +1 more source
Nanotechnology ReviewsAtherosclerosis (AS) is a chronic inflammatory disease that leads to the formation of atherosclerotic plaques in arterial walls, which can eventually result in cardiovascular diseases.
Zheng Lei +13 more
doaj +1 more source