Results 91 to 100 of about 177,791 (315)
Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke +5 more
wiley +1 more source
Reliability of an interneuron response depends on an integrated sensory state
eLife, 2019 The central nervous system transforms sensory information into representations that are salient to the animal. Here we define the logic of this transformation in a Caenorhabditis elegans integrating interneuron.
May Dobosiewicz +2 more
doaj +1 more source
An Ultra-Low-Power Front-End Neural Interface with Automatic Gain for Uncalibrated Monitoring [PDF]
, 2012 This paper presents a dynamic front-end towards achieving unsupervised single-neuron activity monitoring. By implementing at the front-end, an automatic gain control that is optimised for neural signal dynamics, subsequent processing can be achieved ...
Timothy G. Constandinou +3 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub +24 more
wiley +1 more source
Problematic Internet Use in Frontotemporal Dementia: A Case Series
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The present study investigated problematic internet use (PIU) among 61 patients with frontotemporal dementia (FTD) compared to a cohort of 354 patients with mild cognitive impairment (MCI) and Alzheimer's dementia. PIU was identified in 22.9% of FTD patients compared to only 0.8% of AD patients (p < 0.001). Behaviors included compulsive social
Daniele Urso +9 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +16 more
wiley +1 more source
Experience-Induced Neural Circuits That Achieve High Capacity [PDF]
, 2010 Over a lifetime cortex performs a vast number of different cognitive actions, mostly dependent on past experience. Previously it has not been known how such capabilities can be reconciled, even in principle, with the known resource constraints on cortex,
Feldman, Vitaly, Valiant, Leslie
core +1 more source
Causal Neural Probabilistic Circuits
CoRRConcept Bottleneck Models (CBMs) enhance the interpretability of end-to-end neural networks by introducing a layer of concepts and predicting the class label from the concept predictions. A key property of CBMs is that they support interventions, i.e., domain experts can correct mispredicted concept values at test time to improve the final accuracy ...
Weixin Chen, Han Zhao
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source