Results 71 to 80 of about 177,791 (315)
On evolution of relatively large combinational logic circuits
, 2005 Evolvable hardware (EHW) (Yao and Higuchi, 1999) is a technique introduced to automatically design circuits where the circuit configuration is carried out by evolutionary algorithms.
Yatskevich, Y +9 more
core +1 more source
The neural circuits of thermal perception [PDF]
Current Opinion in Neurobiology, 2018 Thermal information about skin surface temperature is a key sense for the perception of object identity and valence. The identification of ion channels involved in the transduction of thermal changes has provided a genetic access point to the thermal system.
Bokiniec, Phillip +3 more
openaire +4 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye +11 more
wiley +1 more source
A Circuit for Gradient Climbing in C. elegans Chemotaxis
Cell Reports, 2015 Animals have a remarkable ability to track dynamic sensory information. For example, the nematode Caenorhabditis elegans can locate a diacetyl odor source across a 100,000-fold concentration range.
Johannes Larsch +5 more
doaj +1 more source
eLife, 2020 Dietary magnesium (Mg2+) supplementation can enhance memory in young and aged rats. Memory-enhancing capacity was largely ascribed to increases in hippocampal synaptic density and elevated expression of the NR2B subunit of the NMDA-type glutamate ...
Yanying Wu +5 more
doaj +1 more source
Equilibrium analysis of cellular neural networks [PDF]
, 2004 Cellular neural networks are dynamical systems, described by a large set of coupled nonlinear differential equations. The equilibrium point analysis is an important step for understanding the global dynamics and for providing design rules. We yield a set
Checco, P. +3 more
core +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Drug-induced change in transmitter identity is a shared mechanism generating cognitive deficits
Nature CommunicationsCognitive deficits are long-lasting consequences of drug use, yet the convergent mechanism by which classes of drugs with different pharmacological properties cause similar deficits is unclear. We find that both phencyclidine and methamphetamine, despite
Marta Pratelli +7 more
doaj +1 more source