Results 41 to 50 of about 180,626 (262)

Stable and dynamic representations of value in the prefrontal cortex

open access: yeseLife, 2020
Optimal decision-making requires that stimulus-value associations are kept up to date by constantly comparing the expected value of a stimulus with its experienced outcome.
Pierre Enel, Joni D Wallis, Erin L Rich
doaj   +1 more source

NEURAL CODES AND NEURAL RING ENDOMORPHISMS

open access: yesRocky Mountain Journal of Mathematics
22 pages, 6 figures and 9 ...
Gupta, Neha, Suhith, K. N.
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Another Neural Code?

open access: yesNeuroImage, 1997
This paper presents the conjecture that functional integration may be mediated by the mutual induction and maintenance of stereotyped spatiotemporal patterns of activity (i.e., transients) in different neuronal populations. In contradistinction to temporal and rate coding models of neuronal interactions, transient coding considers that transactions ...
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Aberration correction in long GRIN lens-based microendoscopes for extended field-of-view two-photon imaging in deep brain regions

open access: yeseLife
Two-photon (2P) fluorescence imaging through gradient index (GRIN) lens-based endoscopes is fundamental to investigate the functional properties of neural populations in deep brain circuits.
Andrea Sattin   +8 more
doaj   +1 more source

Changes in Neuronal Representations of Consonants in the Ascending Auditory System and Their Role in Speech Recognition

open access: yesFrontiers in Neuroscience, 2018
A fundamental task of the ascending auditory system is to produce representations that facilitate the recognition of complex sounds. This is particularly challenging in the context of acoustic variability, such as that between different talkers producing
Mark A. Steadman   +2 more
doaj   +1 more source

Neural Decoder for Topological Codes

open access: yesPhysical Review Letters, 2017
We present an algorithm for error correction in topological codes that exploits modern machine learning techniques. Our decoder is constructed from a stochastic neural network called a Boltzmann machine, of the type extensively used in deep learning.
Torlai, Giacomo, Melko, Roger G.
openaire   +4 more sources

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Navigating the Neural Space in Search of the Neural Code [PDF]

open access: yesNeuron, 2017
The advent of powerful perturbation tools, such as optogenetics, has created new frontiers for probing causal dependencies in neural and behavioral states. These approaches have significantly enhanced the ability to characterize the contribution of different cells and circuits to neural function in health and disease.
Mehrdad, Jazayeri, Arash, Afraz
openaire   +2 more sources

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