Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/β-catenin signalling in the anterior neural patterning of adherent human embryonic stem cell cultures [PDF]
Several studies have successfully produced a variety of neural cell types from human embryonic stem cells (hESCs), but there has been limited systematic analysis of how different regional identities are established using well-defined differentiation ...
Giuseppe Lupo +8 more
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Neural and Neurochemical Mechanisms of Pain Inhibition [PDF]
Recent studies which suggest the existence of an endogenous neural substrate of pain inhibition are reviewed. Electrical stimulation of some areas of the medial brain stem in laboratory rats has produced a dramatic degree of analgesia. Such stimulation-produced analgesia is partially blocked by an opiate antagonist drug.
J C, Liebeskind, J E, Sherman, T, Cannon
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Dynamic neural field with local inhibition [PDF]
A lateral-inhibition type neural field model with restricted connections is presented here and represents an experimental extension of the continuum neural field theory (CNFT) by suppression of the global inhibition. A modified CNFT equation is introduced and allows for a locally defined inhibition to spatially expand within the network and results in ...
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Altered functioning of the inhibition system and the resulting higher impulsivity are known to play a major role in overeating. Considering the great impact of disinhibited eating behavior on obesity onset and maintenance, this systematic review of the ...
Elodie Saruco, Burkhard Pleger
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Decorrelation by Recurrent Inhibition in Heterogeneous Neural Circuits [PDF]
The activity of neurons is correlated, and this correlation affects how the brain processes information. We study the neural circuit mechanisms of correlations by analyzing a network model characterized by strong and heterogeneous interactions: excitatory input drives the fluctuations of neural activity, which are counterbalanced by inhibitory ...
Alberto Bernacchia, Xiao-Jing Wang
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Anti-Neural-Inhibition: A Conserved Mechanism for Neural Induction [PDF]
While the previous discussion highlights the striking degree of evolutionary conservation in the mechanism for partitioning the ectoderm into neural versus nonneural components, it is not as clear that other aspects of D/V patterning have been conserved.
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EEG Asymmetry and ERN: Behavioral Outcomes in Preschoolers.
Research has documented reciprocal influences between approach-related and inhibition-related neural activity in adults. However, associations between neural systems of approach and inhibition have not been tested in children.
J Patrick Begnoche +2 more
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Dendritic Inhibition Enhances Neural Coding Properties [PDF]
The presence of a large number of inhibitory contacts at the soma and axon initial segment of cortical pyramidal cells has inspired a large and influential class of neural network model that use post-integration lateral inhibition as a mechanism for competition between nodes.
Spratling, M W, Johnson, M H
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Neural Correlates of Attentional Modulation of Prepulse Inhibition [PDF]
Prepulse inhibition (PPI) refers to the suppression of the startle reflex when the intense startling stimulus is shortly (20–500 ms) preceded by a weak non-startling stimulus (prepulse). Although the main neural correlates of PPI lie in the brainstem, previous research has revealed that PPI can be top-down modulated by attention.
Ming Lei, Yu Ding, Qingxin Meng
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Disinhibition of somatostatin interneurons confers resilience to stress in male but not female mice
Chronic stress represents a vulnerability factor for anxiety and depressive disorders and has been widely used to model aspects of these disorders in rodents.
Sarah J. Jefferson +5 more
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