Results 41 to 50 of about 322,061 (265)

Neural representations of emotional response inhibition reveal trait and state biomarkers in pediatric bipolar disorder

NeuroImage
Pediatric bipolar disorder (PBD) is characterized by disrupted cognitive control, particularly in response inhibition under emotional interference.
Jia Li, Rong Wang, Jianze Wu, Qian Xiao, Yuan Zhong   +4 more
doaj   +1 more source

Decoding developmental differences and individual variability in response inhibition through predictive analyses across individuals

Frontiers in Human Neuroscience, 2010
Response inhibition is thought to improve throughout childhood and into adulthood. Despite the relationship between age and the ability to stop ongoing behavior, questions remain regarding whether these age-related changes reflect improvements in ...
Jessica R Cohen, Robert F Asarnow, Fred W Sabb, Fred W Sabb, Robert M Bilder, Robert M Bilder, Robert M Bilder, Susan Y Bookheimer, Susan Y Bookheimer, Susan Y Bookheimer, Barbara J Knowlton, Barbara J Knowlton, Russell A Poldrack, Russell A Poldrack, Russell A Poldrack   +14 more
doaj   +1 more source

An exploratory study of functional brain activation underlying response inhibition in major depressive disorder and borderline personality disorder.

PLoS ONE, 2023
Cognitive control is associated with impulsive and harmful behaviours, such as substance abuse and suicidal behaviours, as well as major depressive disorder (MDD) and borderline personality disorder (BPD). The association between MDD and BPD is partially
Cody Cane, Dean Carcone, Katherine Gardhouse, Andy C H Lee, Anthony C Ruocco   +4 more
doaj   +1 more source

Endogenous Inhibition and the Neural Basis of “Free Won't” [PDF]

The Journal of Neuroscience, 2007
Every day we perform thousands of actions and, although we might pay little attention to them, we take for granted that they are mostly generated by our will. In other words, we seem to believe in the existence of a “free will” as an inner causal agent of our behavior.
openaire   +4 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Using Neural Networks for Corrosion Inhibition Efficiency Prediction during Corrosion of Steel in Chloride Solutions

International Journal of Electrochemical Science, 2013
In spite of the huge success that has been attributed to the use of computational chemistry in corrosion studies, most of the ongoing research on the inhibition potential of organic inhibitors is restricted to laboratory work.
K.F. Khaled, Abdelmounam Sherik
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Neural Markers of Inhibition in Human Memory Retrieval [PDF]

The Journal of Neuroscience, 2008
Retrieving particular information from memory facilitates the later retrieval of that information, but also impairs the later retrieval of related, interfering information. It has been theorized that this retrieval-induced forgetting reflects inhibition of interfering memory representations.
Wimber, Maria, Bäuml, Karl-Heinz, Bergström, Zara M, Markopoulos, Gerasimos, Heinze, Hans-Jochen, Richardson-Klavehn, Alan   +5 more
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source