Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/β-catenin signalling in the anterior neural patterning of adherent human embryonic stem cell cultures [PDF]
Open Biology, 2013 Several studies have successfully produced a variety of neural cell types from human embryonic stem cells (hESCs), but there has been limited systematic analysis of how different regional identities are established using well-defined differentiation ...
Giuseppe Lupo +8 more
doaj +1 more source
Disinhibition of somatostatin interneurons confers resilience to stress in male but not female mice
Neurobiology of Stress, 2020 Chronic stress represents a vulnerability factor for anxiety and depressive disorders and has been widely used to model aspects of these disorders in rodents.
Sarah J. Jefferson +5 more
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Frontiers in Neuroscience, 2022 New tools for monitoring and manipulating neural activity have been developed with steadily improving functionality, specificity, and reliability, which are critical both for mapping neural circuits and treating neurological diseases. This review focuses
Junqi Zhuo +9 more
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Engaging and disengaging recurrent inhibition coincides with sensing and unsensing of a sensory stimulus [PDF]
, 2017 Even simple sensory stimuli evoke neural responses that are dynamic and complex. Are the temporally patterned neural activities important for controlling the behavioral output? Here, we investigated this issue.
Altan, Ege +10 more
core +2 more sources
Changes in BOLD variability are linked to the development of variable response inhibition
NeuroImage, 2021 Research on the development of response inhibition in humans has focused almost exclusively on average stopping performance. The development of intra-individual variability in stopping performance and its underlying neural circuitry has remained largely ...
Abigail Thompson +2 more
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Dynamic neural field with local inhibition [PDF]
Biological Cybernetics, 2005 A lateral-inhibition type neural field model with restricted connections is presented here and represents an experimental extension of the continuum neural field theory (CNFT) by suppression of the global inhibition. A modified CNFT equation is introduced and allows for a locally defined inhibition to spatially expand within the network and results in ...
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Neural inhibition enables selection during language processing [PDF]
Proceedings of the National Academy of Sciences, 2010 Whether grocery shopping or choosing words to express a thought, selecting between options can be challenging, especially for people with anxiety. We investigate the neural mechanisms supporting selection during language processing and its breakdown in anxiety.
Snyder, Hannah R. +6 more
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EEG Asymmetry and ERN: Behavioral Outcomes in Preschoolers.
PLoS ONE, 2016 Research has documented reciprocal influences between approach-related and inhibition-related neural activity in adults. However, associations between neural systems of approach and inhibition have not been tested in children.
J Patrick Begnoche +2 more
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Impaired response inhibition and excess cortical thickness as candidate endophenotypes for trichotillomania. [PDF]
, 2014 Trichotillomania is characterized by repetitive pulling out of one's own hair. Impaired response inhibition has been identified in patients with trichotillomania, along with gray matter density changes in distributed neural regions including frontal ...
Chamberlain, Samuel R. +4 more
core +3 more sources
Anti-Neural-Inhibition: A Conserved Mechanism for Neural Induction [PDF]
Cell, 1997 While the previous discussion highlights the striking degree of evolutionary conservation in the mechanism for partitioning the ectoderm into neural versus nonneural components, it is not as clear that other aspects of D/V patterning have been conserved.
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