Results 81 to 90 of about 446,619 (318)
Fine Discrimination of Analog Patterns by Nonlinear Dendritic Inhibition [PDF]
arXiv, 2004 Recent experiments revealed that a certain class of inhibitory neurons in the cerebral cortex make synapses not onto cell bodies but at distal parts of dendrites of the target neurons, mediating highly nonlinear dendritic inhibition. We propose a novel form of competitive neural network model that realizes such dendritic inhibition.
arxiv
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Stage-specific roles of FGF2 signaling in human neural development
Stem Cell Research, 2016 This study elucidated the stage-specific roles of FGF2 signaling during neural development using in-vitro human embryonic stem cell-based developmental modeling.
Marta Grabiec +6 more
doaj +1 more source
Global Neural Activities Changes under Human Inhibitory Control Using Translational Scenario
Brain Sciences, 2020 This study presents a new approach to exploring human inhibition in a realistic scenario. In previous inhibition studies, the stimulus design of go/no-go task generally used a simple symbol for the go and stop signals.
Rupesh Kumar Chikara, Li-Wei Ko
doaj +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
The role of competitive inhibition and top-down feedback in binding during object recognition
Frontiers in Psychology, 2012 How does the brain bind together visual features that are processed concurrently by different neurons into a unified percept suitable for processes such as object recognition?
Dean eWyatte +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
NeuroImage, 2022 Inhibitory control, a core executive function, emerges in infancy and develops rapidly across childhood. Methodological limitations have meant that studies investigating the neural correlates underlying inhibitory control in infancy are rare.
Abigail Fiske +9 more
doaj
Speaking Two Languages Enhances an Auditory but Not a Visual Neural Marker of Cognitive Inhibition
AIMS Neuroscience, 2014 The purpose of the present study was to replicate and extend our original findings of enhanced neural inhibitory control in bilinguals. We compared English monolinguals to Spanish/English bilinguals on a non-linguistic, auditory Go/NoGo task while ...
Mercedes Fernandez +4 more
doaj +1 more source
Surround Inhibition Mechanism by Deep Learning [PDF]
arXiv, 2019 In the sensation of tones, visions and other stimuli, the "surround inhibition mechanism" (or "lateral inhibition mechanism") is crucial. The mechanism enhances the signals of the strongest tone, color and other stimuli, by reducing and inhibiting the surrounding signals, since the latter signals are less important.
arxiv