Results 91 to 100 of about 9,277,012 (302)

Postsynaptic density protein 95 (PSD-95) is transported by KIF5 to dendritic regions

open access: yesMolecular Brain, 2019
Postsynaptic density protein 95 (PSD-95) is a pivotal postsynaptic scaffolding protein in excitatory neurons. Although the transport and regulation of PSD-95 in synaptic regions is well understood, dendritic transport of PSD-95 before synaptic ...
Ki-Seo Yoo   +6 more
doaj   +1 more source

Genetically Generated Neural Networks I: Representational Effects [PDF]

open access: yes, 1992
This paper studies several applications of genetic algorithms (GAs) within the neural networks field. After generating a robust GA engine, the system was used to generate neural network circuit architectures.
Marti, Leonardo
core   +2 more sources

Back-propagation optimization and multi-valued artificial neural networks for highly vivid structural color filter metasurfaces [PDF]

open access: gold, 2023
Arthur Clini de Souza   +6 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Active noise control algorithm based on a neural network and nonlinear input-output system identification model

open access: yesArchives of Acoustics, 2013
The development of digital signal processors and the increase in their computing capabilities bring opportunities to employ algorithms with multiple variable parameters in active noise control systems.
Tomasz KRUKOWICZ
doaj  

Modelling Identity Rules with Neural Networks [PDF]

open access: yes, 2019
In this paper, we show that standard feed-forward and recurrent neural networks fail to learn abstract patterns based on identity rules. We propose Repetition Based Pattern (RBP) extensions to neural network structures that solve this problem ...
Kopparti, R. M., Weyde, T.
core   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Application of Quantum Genetic Optimization of LVQ Neural Network in Smart City Traffic Network Prediction

open access: yesIEEE Access, 2020
Accurate prediction of traffic flow in urban networks is of great significance for smart city management. A short-term traffic flow prediction algorithm of Quantum Genetic Algorithm - Learning Vector Quantization (QGA-LVQ) neural network is proposed to ...
Fuquan Zhang   +6 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Functional Connectivity Associations With Markers of Disease Progression in GRN Pathogenic Variant Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autosomal dominant progranulin (GRN) pathogenic variants are a genetic cause of frontotemporal lobar degeneration. Though clinical trials for GRN‐related therapies are underway, there is an unmet need for biomarkers that can predict symptom onset and track disease progression.
Taru M. Flagan   +46 more
wiley   +1 more source

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