Results 111 to 120 of about 2,988,540 (294)

Harmony in the brain: A narrative review on the shared neural substrates of emotion regulation and creativity

open access: yesBrain Organoid and Systems Neuroscience Journal
The contribution of creativity in overall well-being through regulating emotions has sparkled research interest in employing artistic interventions recently for the improvement of mental health.
A.I. Ladas   +3 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Bypassing stroke-damaged neural pathways via a neural interface induces targeted cortical adaptation

open access: yesNature Communications, 2019
Monkeys were trained to use an artificial cortico-muscular connection (ACMC) to regain control over a paralyzed hand following subcortical stroke. Control over the paralyzed hand was accompanied by the appearance of localized high-gamma modulation in the 
Kenji Kato   +2 more
doaj   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Efeito do FGF2 na diferenciação de células da crista neural truncal (CNT) de codornas in vitro [PDF]

open access: yes, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciencias Biológicas. Programa de Pós-Graduação em Neurociências.As células da crista neural (CN) têm origem a partir das bordas entre a placa neural e a epiderme durante o ...
Bittencourt, Denise Avani
core  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Can a competitive neural network explain selective attention in insect target tracking neurons?

open access: yes, 2013
Small target motion detecting (STMD) neurons in the dragonfly brain are neural correlates of a highly-specialized and ethologically-significant feature detection function, and the recent discovery of selective attention in STMDs has clear implications ...
Steven D. Wiederman   +5 more
core   +1 more source

Central Neural Pathways Controlling Skeletal Muscle Shivering

open access: yesRevista Cubana de Investigaciones Biomédicas, 2020
Introduction: Skeletal muscle shivering is the most important source of thermogenesis in the human cold-defensive maintenance of core body temperature (Tcore) and the elevated Tcore during fever. The thermoregulatory reflex pathway through which skin and
Shaun F. Morrison   +1 more
doaj  

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Transcriptome-wide regulation of folate on neural mRNA m6A methylome via carbon metabolism in Drosophila and mammals

open access: yesCommunications Biology
Increasing evidence shows that folate can regulate neural gene function through DNA modification, while regulatory roles of folate in neural RNA modification remain largely unknown.
Anrui Liu   +10 more
doaj   +1 more source

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