Results 91 to 100 of about 3,455,773 (294)
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Acta OrthopaedicaBackground and purpose: Distal radius fractures (DRFs) are common in older adults and are associated with osteoporosis and underlying frailty. While hip and spine fractures are associated with increased mortality, the association between DRFs and all ...
Cecilie Rud Budtz +5 more
doaj +1 more source
Neural electrical activity and neural network growth [PDF]
, 2018 © 2018 Elsevier Ltd The development of central and peripheral neural system depends in part on the emergence of the correct functional connectivity in its input and output pathways.
core
Neural stem cells in Drosophila : molecular genetic mechanisms underlying normal neural proliferation and abnormal brain tumor formation [PDF]
, 2012 Neural stem cells in Drosophila are currently one of the best model systems for understanding stem cell biology during normal development and during abnormal development of stem cell-derived brain tumors.
Heinrich Reichert +5 more
core +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Two Distinct Neural Pathways for Mechanical versus Digital Technology
Data and codes for Federico et al. (2024). Two Distinct Neural Pathways for Mechanical versus Digital Technology.
François Osiurak +12 more
core +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Neural Mechanisms and Pathways in Craniofacial Pain [PDF]
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1999 Many free nerve endings of small-diameter afferents (A-delta or C nerve fibres) respond to craniofacial noxious stimuli and a number of neurochemicals are involved in their activation or sensitization. The small-diameter nociceptive afferents project to the trigeminal (V) brainstem complex where they can excite nociceptive neurones that have been ...
openaire +2 more sources
Neural Pathways of Sexual Arousal [PDF]
, 2013 Recent research in neuroscience and psychology has suggested significant differences in sexual arousal between genders. In this review, the neuroscience evidence for gender differences in sexual arousal is investigated and current psychological theories ...
Hall, Ashley
core
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source