Results 241 to 250 of about 1,681,568 (307)

A novel OTUD5 variant disrupts neural progenitor cell homeostasis: mechanistic insights from HEK293T cell-based analyses. [PDF]

Stem Cell Res Ther
Xu N, Wang S, Yang T, Yu M, Sun Y, Zhan Y, Yu Y.   +6 more
europepmc   +1 more source

Integrating chemo‐mechanical cues in nano‐microscale environments for stem cell regulation

BMEMat, EarlyView.
Nano/microscale control strategies, including nano/microscale materials, ligand spacings, and cell encapsulating gels, cell mechanics, integrin signaling, and biochemical cues to direct stem cell fate, tissue regeneration, and organoid engineering, enabling advanced biomedical applications through mechanoregulation at cell‐material interfaces ...
Rajendra K. Singh, Varsha Sagar, Amal George Kurian, Shreyas Kumar Jain, Hye Sung Kim, Hae‐Won Kim   +5 more
wiley   +1 more source

Loss of SETDB1-mediated H3K9me3 in human neural progenitor cells leads to transcriptional activation of L1 retrotransposons. [PDF]

Nucleic Acids Res
Karlsson O, Pandiloski N, Horvath V, Adami A, Garza R, Johansson PA, Johansson JG, Douse CH, Jakobsson J.   +8 more
europepmc   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source

Axial Identity of Spinal Cord Neural Progenitor Cell Grafts Is Dispensable for Regeneration and Functional Recovery After Spinal Cord Injury. [PDF]

Cells
Smith A, Dietz V, Hoppe JD, Imrie G, Lee G, Leonards A, Jagrit V, Evans A, Gillespie T, Gottschall B, Inskeep B, Amar Kumar P, Friedrich L, Blackmore MG, Farhy-Tselnicker I, Dulin JN.   +15 more
europepmc   +1 more source

Substrate stiffness regulates cell fate and its applications in the repair of motor system: From two dimensions to three dimensions

BMEMat, EarlyView.
Substrate stiffness with different dimensions (2D and 3D) exerts a regulatory role in cellular behaviors, thereby governing cell fate decisions. Biomaterials with tunable stiffness exhibit substantial functional potential for the repair and regeneration of the motor system.
Zhiyuan Lu, Renwang Sheng, Ludvig J. Backman, Chuanquan Liu, Danning Zheng, Wei Zhang, Jialin Chen   +6 more
wiley   +1 more source

Potential of immortalized neural progenitor

Cell Transplantation, 1996
openaire   +1 more source

Dynamic transcriptomic remodeling in grafted human neural progenitor cells uncovers mechanisms for vision preservation in a rat model of retinitis pigmentosa. [PDF]

Nat Commun
Shahin S, Bell S, Lu B, Banerjee S, Swarup V, Xu H, Chetsawang J, Ramirez S, Alfaro JS, Laperle A, Svendsen S, Svendsen CN, Wang S.   +12 more
europepmc   +1 more source

Harnessing bacterial extracellular vesicles for bone and cartilage organoids

BMEMat, EarlyView.
This review presents bacterial extracellular vesicles (BEVs) as programmable bioactive regulators for bone and cartilage organoids by delivering functional cargos that modulate skeletal remodeling. It highlights key engineering strategies and future directions to advance next‐generation organoid models for bone aging related diseases.
Han Liu, Xukun Lv, Ting Cheng, Lei Yan, Yuxiao Lai, Keying Guo, Yingying Jing, Hao Shen, Jiacan Su   +8 more
wiley   +1 more source

Phase separated condensates of ATRX regulate neural progenitor identity. [PDF]

Nat Commun
Tomooka R, Sanosaka T, Miyagi T, Andoh-Noda T, Banno S, Mizota N, Kanekura K, Okano H, Kohyama J.   +8 more
europepmc   +1 more source