Results 21 to 30 of about 1,843,588 (298)

Characterizing the Retinal Phenotype of the Thy1-h[A30P]α-syn Mouse Model of Parkinson’s Disease

Frontiers in Neuroscience, 2021
Despite decades of research, disease-modifying treatments of Parkinson’s disease (PD), the second most common neurodegenerative disease worldwide, remain out of reach.
Lien Veys, Lien Veys, Joyce Devroye, Joyce Devroye, Evy Lefevere, Evy Lefevere, Lien Cools, Lien Cools, Marjan Vandenabeele, Marjan Vandenabeele, Lies De Groef, Lies De Groef   +11 more
doaj   +1 more source

An evolutionary AI-based decision support system for urban regeneration planning [PDF]

, 2010
A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the Degree of Doctor of PhilosophyThe renewal of derelict inner-city urban districts suffering from high levels of socio-economic deprivation and ...
Yusuf, Syed Adnan
core   +3 more sources

Retinal Ganglion Cells: Global Number, Density and Vulnerability to Glaucomatous Injury in Common Laboratory Mice

Cells, 2022
How many RBPMS+ retinal ganglion cells (RGCs) does a standard C57BL/6 laboratory mouse have on average and is this number substrain- or sex-dependent? Do RGCs of (European) C57BL/6J and -N mice show a different intrinsic vulnerability upon glaucomatous ...
Marie Claes, Lieve Moons
doaj   +1 more source

Prior Exposure to Immunosuppressors Sensitizes Retinal Microglia and Accelerates Optic Nerve Regeneration in Zebrafish

Mediators of Inflammation, 2019
As adult mammals lack the capacity to replace or repair damaged neurons, degeneration and trauma (and subsequent dysfunction) of the central nervous system (CNS) seriously constrains the patient’s life quality.
Ilse Bollaerts, Jessie Van houcke, An Beckers, Kim Lemmens, Sophie Vanhunsel, Lies De Groef, Lieve Moons   +6 more
doaj   +1 more source

Ischemic postconditioning protects against acute kidney injury after limb ischemia reperfusion by regulating HMGB1 release and autophagy

Renal Failure, 2023
Ischemic postconditioning (I-PostC) has a protective effect against acute kidney injury (AKI) induced by limb ischemia–reperfusion (LIR); however, the exact mechanism remains to be elucidated.
Zhongdi Liu, Yifan Chen, Zhe Du, Fengxue Zhu, Wei Huang   +4 more
doaj   +1 more source

Glycogen synthase kinase 3 signaling in neural regeneration in vivo [PDF]

Journal of Molecular Cell Biology
Fengquan Zhou, Zhen-Ge Luo
exaly   +2 more sources

Women in visual neural regeneration research. [PDF]

Neural Regen Res
Rex TS, Calkins DJ.
europepmc   +4 more sources

Neurochemical metabolites in the medial prefrontal cortex in bipolar disorder: A proton magnetic resonance spectroscopy study

, 2012
The aim of this study was to investigate proton magnetic resonance spectroscopy metabolite values in the medial prefrontal cortex of individuals with euthymic bipolar disorder.
Kalayci, D., Tümkaya, Selim, Özdel, Osman İsmail, Toker-Uğurlu, Tuğçe, Kıroğlu, Yılmaz, Sözeri-Varma, Gülfizar   +5 more
core   +1 more source

Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neurons

Acta Neuropathologica Communications, 2023
The multifaceted nature of neuroinflammation is highlighted by its ability to both aggravate and promote neuronal health. While in mammals retinal ganglion cells (RGCs) are unable to regenerate following injury, acute inflammation can induce axonal ...
Lien Andries, Daliya Kancheva, Luca Masin, Isabelle Scheyltjens, Hannah Van Hove, Karen De Vlaminck, Steven Bergmans, Marie Claes, Lies De Groef, Lieve Moons, Kiavash Movahedi   +10 more
doaj   +1 more source

Effects of resveratrol on hydrogen peroxide-induced oxidative stress in embryonic neural stem cells

, 2013
Resveratrol, a natural phenolic compound, has been shown to prevent cardiovascular diseases and cancer and exhibit neuroprotective effects. In this study, we examined the neuroprotective and antioxidant effects of resveratrol against hydrogen peroxide in
Armagan, Guliz, Atalayin, Cigdem, Yalcin, Ayfer, Dagci, Taner, Konyalioglu, Sibel   +4 more
core   +1 more source