Results 31 to 40 of about 215,731 (353)

The effects of age and ganglioside composition on the rate of motor nerve terminal regeneration following antibody-mediated injury in mice [PDF]

open access: yes, 2013
Gangliosides are glycosphingolipids highly enriched in neural plasma membranes, where they mediate a diverse range of functions and can act as targets for auto-antibodies present in human immune-mediated neuropathy sera.
Cunningham, Madeleine E.   +4 more
core   +1 more source

Enhancing Nervous System Recovery through Neurobiologics, Neural Interface Training, and Neurorehabilitation. [PDF]

open access: yes, 2016
After an initial period of recovery, human neurological injury has long been thought to be static. In order to improve quality of life for those suffering from stroke, spinal cord injury, or traumatic brain injury, researchers have been working to ...
Edgerton, V Reggie   +4 more
core   +1 more source

Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neurons

open access: yesActa Neuropathologica Communications, 2023
The multifaceted nature of neuroinflammation is highlighted by its ability to both aggravate and promote neuronal health. While in mammals retinal ganglion cells (RGCs) are unable to regenerate following injury, acute inflammation can induce axonal ...
Lien Andries   +10 more
doaj   +1 more source

Metabotropic Glutamate Receptors 1 Regulates Rat Carotid Body Response to Acute Hypoxia via Presynaptic Mechanism

open access: yesFrontiers in Neuroscience, 2021
Background: The carotid body (CB) plays a critical role in oxygen sensing; however, the role of glutamatergic signaling in the CB response to hypoxia remains uncertain.
Chaohong Li   +4 more
doaj   +1 more source

Influence of Biphasic Stimulation on Olfactory Ensheathing Cells for Neuroprosthetic Devices [PDF]

open access: yes, 2016
The recent success of olfactory ensheathing cell (OEC) assisted regeneration of injured spinal cord has seen a rising interest in the use of these cells in tissue-engineered systems.
Foster, LJR, Green, RA, Hassarati, RT
core   +1 more source

Harnessing the power of cell transplantation to target respiratory dysfunction following spinal cord injury. [PDF]

open access: yes, 2017
The therapeutic benefit of cell transplantation has been assessed in a host of central nervous system (CNS) diseases, including disorders of the spinal cord such as traumatic spinal cord injury (SCI).
Charsar, Brittany A.   +2 more
core   +2 more sources

The DREADDful Hurdles and Opportunities of the Chronic Chemogenetic Toolbox

open access: yesCells, 2022
The chronic character of chemogenetics has been put forward as one of the assets of the technique, particularly in comparison to optogenetics. Yet, the vast majority of chemogenetic studies have focused on acute applications, while repeated, long-term ...
Marie Claes, Lies De Groef, Lieve Moons
doaj   +1 more source

Stem and progenitor cells: Origins, phenotypes, lineage commitments, and transdifferentiations [PDF]

open access: yes, 2001
Multipotent stem cells are clonal cells that self-renew as well as differentiate to regenerate adult tissues. Whereas stem cells and their fates are known by unique genetic marker studies, the fate and function of these cells are best studied by their ...
Anderson­, David J.   +2 more
core   +1 more source

The superiority of conditioned medium derived from rapidly expanded mesenchymal stem cells for neural repair

open access: yesStem Cell Research & Therapy, 2019
s Background Spinal cord injury (SCI) is a complex and severe neurological condition. Mesenchymal stem cells (MSCs) and their secreted factors show promising potential for regenerative medicine.
Ya-Tzu Chen   +6 more
doaj   +1 more source

The Application of Brain Organoids in Assessing Neural Toxicity

open access: yesFrontiers in Molecular Neuroscience, 2022
The human brain is a complicated and precisely organized organ. Exogenous chemicals, such as pollutants, drugs, and industrial chemicals, may affect the biological processes of the brain or its function and eventually lead to neurological diseases ...
Pan Fan   +5 more
doaj   +1 more source

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