Results 11 to 20 of about 1,045,843 (356)
Flexibility of Neural Stem Cells [PDF]
Frontiers in Physiology, 2011 Embryonic cortical neural stem cells are self-renewing progenitors that can differentiate into neurons and glia. We generated neurospheres from the developing cerebral cortex using a mouse genetic model that allows for lineage selection and found that the self-renewing neural stem cells are restricted to Sox2 expressing cells.
Remboutsika, Eumorphia +7 more
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APL Bioengineering, 2023 During embryonic development, endothelial cells (ECs) undergo vasculogenesis to form a primitive plexus and assemble into networks comprised of mural cell-stabilized vessels with molecularly distinct artery and vein signatures. This organized vasculature
Taylor Bertucci +9 more
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The Effects of Extrinsic and Intrinsic Factors on Neurogenesis
Cells, 2023 In the mammalian brain, neurogenesis is maintained throughout adulthood primarily in two typical niches, the subgranular zone (SGZ) of the dentate gyrus and the subventricular zone (SVZ) of the lateral ventricles and in other nonclassic neurogenic areas (
Mei Jiang, Se Eun Jang, Li Zeng
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Neural Stem Cell Transplantation for Neurodegenerative Diseases
International Journal of Molecular Sciences, 2020 Neurodegenerative diseases are disabling and fatal neurological disorders that currently lack effective treatment. Neural stem cell (NSC) transplantation has been studied as a potential therapeutic approach and appears to exert a beneficial effect ...
Roberta De Gioia +8 more
semanticscholar +1 more source
Journal of Neuroinflammation, 2022 Background Alcohol use disorders result from repeated binge and chronic alcohol consumption followed by negative effects, such as anxiety, upon cessation. This process is associated with the activation of NLRP3 inflammasome-mediated responses.
Ziyi Li +9 more
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Depressive patient‐derived GABA interneurons reveal abnormal neural activity associated with HTR2C
EMBO Molecular Medicine, 2022 Major depressive disorder with suicide behavior (sMDD) is a severe mood disorder, bringing tremendous burden to family and society. Although reduced gamma amino butyric acid (GABA) level has been observed in postmortem tissues of sMDD patients, the ...
Kaiqin Lu +11 more
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Neural Stem Cells and Stroke [PDF]
Cell Transplantation, 2013 Acute ischemic stroke causes a disturbance of neuronal circuitry and disruption of the blood–brain barrier that can lead to functional disabilities. At present, thrombolytic therapy inducing recanalization of the occluded vessels in the cerebral infarcted area is a commonly used therapeutic strategy.
Chen Huan Lin +3 more
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, 2008 Neural stem cells (NSCs) are the self-renewing, multipotent cells that generate neurons, astrocytes, and oligodendrocytes in the nervous system. In the fetus, NSCs participate to the development of the nervous system. Stem cells are present in many tissues of adult mammals where they contribute to cellular homeostasis and regeneration after injury. The
Richard L. Sidman +6 more
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The Application of Brain Organoids in Assessing Neural Toxicity
Frontiers in Molecular Neuroscience, 2022 The human brain is a complicated and precisely organized organ. Exogenous chemicals, such as pollutants, drugs, and industrial chemicals, may affect the biological processes of the brain or its function and eventually lead to neurological diseases ...
Pan Fan +5 more
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Journal of Investigative Dermatology Symposium Proceedings, 1997 This article is concerned with the idea that neural precursor cells in vertebrates can self-renew and give rise to all cell types within the nervous system. Supportive evidence for this notion of neural stem cells comes from clonal analyses undertaken both in vivo and in vitro. Neural stem cells also give rise to other cells in the body, including skin
Gordon J.f. Brooker +4 more
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