Identification of a Neural Stem Cell in the Adult Mammalian Central Nervous System [PDF]
Cell, 1999 Clas B. Johansson +5 more
openalex +2 more sources
Deep learning-based predictive identification of neural stem cell differentiation
Nature Communications, 2021 The differentiation of neural stem cells (NSCs) into neurons is proposed to be critical in devising potential cell-based therapeutic strategies for central nervous system (CNS) diseases, however, the determination and prediction of differentiation is ...
Yanjing Zhu +5 more
semanticscholar +1 more source
Control the Neural Stem Cell Fate with Biohybrid Piezoelectrical Magnetite Micromotors.
Nano letters (Print), 2021 Inducing neural stem cells to differentiate and replace degenerated functional neurons represents the most promising approach for neural degenerative diseases including Parkinson's disease, Alzheimer's disease, etc.
Lu Liu +13 more
semanticscholar +1 more source
Electrical Stimulation Promotes Stem Cell Neural Differentiation in Tissue Engineering
Stem Cells International, 2021 Nerve injuries and neurodegenerative disorders remain serious challenges, owing to the poor treatment outcomes of in situ neural stem cell regeneration. The most promising treatment for such injuries and disorders is stem cell-based therapies, but there ...
Hong Cheng +3 more
semanticscholar +1 more source
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation [PDF]
Nature, 2003 Anna V. Molofsky +5 more
openalex +2 more sources
Neural Stem Cell Transplantation for Neurodegenerative Diseases
International Journal of Molecular Sciences, 2020 Neurodegenerative diseases are disabling and fatal neurological disorders that currently lack effective treatment. Neural stem cell (NSC) transplantation has been studied as a potential therapeutic approach and appears to exert a beneficial effect ...
Roberta De Gioia +8 more
semanticscholar +1 more source
Physiological Plasticity of Neural-Crest-Derived Stem Cells in the Adult Mammalian Carotid Body [PDF]
, 2017 Adult stem cell plasticity, or the ability of somatic stem cells to cross boundaries and differentiate into unrelated cell types, has been amatter of debate in the last decade.
Annese, Valentina +3 more
core +7 more sources
Neural Stem Cells and Stroke [PDF]
Cell Transplantation, 2013 Acute ischemic stroke causes a disturbance of neuronal circuitry and disruption of the blood–brain barrier that can lead to functional disabilities. At present, thrombolytic therapy inducing recanalization of the occluded vessels in the cerebral infarcted area is a commonly used therapeutic strategy.
Chen Huan Lin +3 more
openaire +3 more sources
The Application of Brain Organoids in Assessing Neural Toxicity
Frontiers in Molecular Neuroscience, 2022 The human brain is a complicated and precisely organized organ. Exogenous chemicals, such as pollutants, drugs, and industrial chemicals, may affect the biological processes of the brain or its function and eventually lead to neurological diseases ...
Pan Fan +5 more
doaj +1 more source
The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022 Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee +16 more
wiley +1 more source