Results 41 to 50 of about 1,438,323 (398)
The emerging roles of ribosome biogenesis in craniofacial development. [PDF]
, 2014 Neural crest cells (NCCs) are a transient, migratory cell population, which originates during neurulation at the neural folds and contributes to the majority of tissues, including the mesenchymal structures of the craniofacial skeleton.
Ross, Adam P, Zarbalis, Konstantinos S
core +2 more sources
The stem cells of the neural crest [PDF]
Cell Cycle, 2008 In the vertebrate embryo, the neurectodermal neural crest cells (NCC) have remarkably broad potencies, giving rise, after a migratory phase, to neurons and glial cells in the peripheral nervous system, and to skin melanocytes, being all designated here as "neural" derivatives.
Nicole M. Le Douarin +2 more
openaire +3 more sources
Stem Cell Reports, 2017 Age-related macular degeneration (AMD) is a common cause of central visual loss in the elderly. Retinal pigment epithelial (RPE) cell loss occurs early in the course of AMD and RPE cell transplantation holds promise to slow disease progression. We report
Richard J. Davis +18 more
doaj +1 more source
Micro- and nanoengineering approaches to control stem cell-biomaterial interactions. [PDF]
, 2011 As our population ages, there is a greater need for a suitable supply of engineered tissues to address a range of debilitating ailments. Stem cell based therapies are envisioned to meet this emerging need. Despite significant progress in controlling stem
Dokmeci, Mehmet R +4 more
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Neural stem cell transplantation therapy for brain ischemic stroke: Review and perspectives
World Journal of Stem Cells, 2019 Brain ischemic stroke is one of the most common causes of death and disability, currently has no efficient therapeutic strategy in clinic. Due to irreversible functional neurons loss and neural tissue injury, stem cell transplantation may be the most ...
Guilong Zhang, Zhijun Zhu, Ye-Zhong Wang
semanticscholar +1 more source
Using Deep Learning to Predict Neural Stem Cell Differentiation in Regenerative Medicine [PDF]
arXiv, 2023 Over one in three people are affected by neurodegenerative disorders. Neural stem cells, which are multipotent regenerative cells with the potential to differentiate into any of the neural cell types, have immense therapeutic potential for treating neurological disorders.
arxiv
Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival [PDF]
, 2006 There are two types of neural stem cells (NSCs). Primitive NSCs [leukemia inhibitory factor (LIF) dependent but exogenous fibroblast growth factor (FGF) 2 independent] can be derived from mouse embryonic stem (ES) cells in vitro and from embryonic day 5 ...
Chaddah, R +7 more
core +2 more sources
Neural stem cell therapy for subacute and chronic ischemic stroke
Stem cell research & therapeutics, 2018 Neural stem cells (NSCs) play vital roles in brain homeostasis and exhibit a broad repertoire of potentially therapeutic actions following neurovascular injury. One such injury is stroke, a worldwide leading cause of death and disability.
A. Boese +4 more
semanticscholar +1 more source
Defining the role of oxygen tension in human neural progenitor fate. [PDF]
, 2014 Hypoxia augments human embryonic stem cell (hESC) self-renewal via hypoxia-inducible factor 2α-activated OCT4 transcription. Hypoxia also increases the efficiency of reprogramming differentiated cells to a pluripotent-like state. Combined, these findings
Cinkornpumin, Jessica +10 more
core +1 more source
Human neural stem cell transplantation improves cognition in a murine model of Alzheimer’s disease
Scientific Reports, 2018 Stem cell transplantation offers a potentially transformative approach to treating neurodegenerative disorders. The safety of cellular therapies is established in multiple clinical trials, including our own in amyotrophic lateral sclerosis.
Lisa M. McGinley +9 more
semanticscholar +1 more source