Results 51 to 60 of about 431,489 (297)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
STAR Protocols, 2023 Summary: Cerebral organoids represent an optimal experimental system for studying human cortical development, evolution, physiology, function, and disease mechanisms.
Xiao-Yan Tang +4 more
doaj +1 more source
An ependymal cell quest : identification and functional role of spinal cord neural stem cells [PDF]
, 2014 Few injuries have as profound and long-lasting consequences as spinal cord injury. The primary areas of impaired function typically include sensation, mobility, bladder, bowel and sexual function.
Sabelström, Hanna
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Neurobiology of Disease, 2006 Recent evidences suggest key roles of abnormal neurogenesis and astrogliosis in the pathogenesis of epilepsy. Alterations in the microenvironment of the stem cell, such as microglial activation and cyclooxygenase-2 induction may cause ectopic ...
Keun-Hwa Jung +11 more
doaj +1 more source
Evaluation of Dynamic Cell Processes and Behavior Using Video Bioinformatics Tools [PDF]
, 2015 Just as body language can reveal a person’s state of well-being, dynamic changes in cell behavior and morphology can be used to monitor processes in cultured cells.
A Valavanidis +35 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
F1000Research, 2014 Rationale: Choroidal neovascular (CNV) lesions in younger patients are often accompanied by the appearance of a surrounding ring of pigment that is associated with disease regression or slowed disease progression.
Jeffrey Stern +3 more
doaj +1 more source
Shared and Divergent Epigenetic Mechanisms in Cachexia and Sarcopenia
Cells, 2022 Significant loss of muscle mass may occur in cachexia and sarcopenia, which are major causes of mortality and disability. Cachexia represents a complex multi-organ syndrome associated with cancer and chronic diseases.
Laura Yedigaryan +4 more
doaj +1 more source
Identification of a neural crest stem cell niche by Spatial Genomic Analysis [PDF]
, 2017 The neural crest is an embryonic population of multipotent stem cells that form numerous defining features of vertebrates. Due to lack of reliable techniques to perform transcriptional profiling in intact tissues, it remains controversial whether the ...
Bronner, Marianne E. +4 more
core +4 more sources