Results 81 to 90 of about 1,045,843 (356)
Machine Learning and Medical Data: Predicting ICU Mortality and Re-admission Risks
Journal of Advanced Research in Natural and Applied SciencesIntensive care units (ICUs) are divisions where critically ill patients are treated by medical experts. The unmet and vital need for automated clinical decision-making mechanisms is critical to maneuvering the large influx of patients.
Runia Roy, Ulya Bayram
doaj +1 more source
Stem Cell Research & Therapy, 2023 National Eye Institute recently issued a new Strategic Plan outlining priority research areas for the next 5 years. Starting cell source for deriving stem cell lines is as an area with gaps and opportunities for making progress in regenerative medicine ...
Ashley M. Fortress +10 more
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Identification of a neural crest stem cell niche by Spatial Genomic Analysis
Nature Communications, 2017 The neural crest is an embryonic population of multipotent stem cells that form numerous defining features of vertebrates. Due to lack of reliable techniques to perform transcriptional profiling in intact tissues, it remains controversial whether the ...
A. Lignell +4 more
semanticscholar +1 more source
Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024
FEBS Open Bio, EarlyView.The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior +5 more
wiley +1 more source
Stem Cell Reports, 2018 Summary: With stem cell-derived retinal pigment epithelial (RPE) replacement therapies in clinical testing, establishing potency of RPE prior to transplantation is imperative. Phagocytosis of photoreceptor outer segment fragments (POS) is a key indicator
Claudia Müller +3 more
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Molecular Crosstalk Between Circadian Rhythmicity and the Development of Neurodegenerative Disorders
Frontiers in Neuroscience, 2020 Neurodegenerative disorders have been shown to exhibit substantial interconnectedness with circadian rhythmicity. Alzheimer’s patients exhibit high degradation of the suprachiasmatic nucleus (SCN), the central endogenous circadian timekeeper, and ...
Arastu Sharma +5 more
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Stem Cells, Neural Progenitors, and Engineered Stem Cells [PDF]
, 2014 Human pluripotent stem cells (hPSCs ) have the unique potential to form every cell type in the body. This potential provides opportunities for generating human progenitors and other differentiated cell types for understanding human development and for use in cell type-specific therapies. Equally important is the ability to engineer stem cells and their
Shilpa Iyer, Raj R. Rao
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The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
FEBS Open Bio, EarlyView.We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel +8 more
wiley +1 more source
STAR ProtocolsSummary: Midbrain organoids serve as a valuable model for studying brain development and disease. Here, we present a viral infection protocol for midbrain organoid models.
Mengdan Tao +4 more
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eLife, 2016 During the development, tight regulation of the expansion of neural progenitor cells (NPCs) and their differentiation into neurons is crucial for normal cortical formation and function.
Wei Zhang +9 more
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